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Lkb1 orchestrates γδ T-cell metabolic and functional fitness to control IL-17-mediated autoimmune hepatitis

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  1. Article

    Open Access

    Allogeneic Vγ9Vδ2 T-cell immunotherapy exhibits promising clinical safety and prolongs the survival of patients with late-stage lung or liver cancer

    Vγ9Vδ2 T cells are promising candidates for cellular tumor immunotherapy. Due to their HLA-independent mode of action, allogeneic Vγ9Vδ2 T cells can be considered for clinical application. To apply allogeneic ...

    Yan Xu, Zheng **ang, Mohammed Alnaggar, Léonce Kouakanou… in Cellular & Molecular Immunology (2021)

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  2. Article

    Open Access

    Vitamin C promotes the proliferation and effector functions of human γδ T cells

    γδ T cells are of interest as effector cells for cellular immunotherapy due to their HLA-non-restricted lysis of many different tumor cell types. Potential applications include the adoptive transfer of in vitr...

    Léonce Kouakanou, Yan Xu, Christian Peters, Junyi He… in Cellular & Molecular Immunology (2020)

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