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Article
Open AccessSingle-cell landscape of immunocytes in patients with extrahepatic cholangiocarcinoma
The intricate landscape of immunocytes in the tumor microenvironment (TME) is fundamental to immunotherapy but notably under-researched in extrahepatic cholangiocarcinoma (ECCA).
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Article
Open AccessExosomes in the tumor microenvironment of cholangiocarcinoma: current status and future perspectives
Cholangiocarcinoma (CCA) refers to an aggressive malignancy with a high fatality rate and poor prognosis. Globally, the morbidity of CCA is increasing for the past few decades, which has progressed into a dise...
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Article
Open AccessMacrophages-aPKCɩ-CCL5 Feedback Loop Modulates the Progression and Chemoresistance in Cholangiocarcinoma
Recent data indicated that macrophages may mutually interact with cancer cells to promote tumor progression and chemoresistance, but the interaction in cholangiocarcinoma (CCA) is obscure.
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Article
Application of convolutional neural network in predicting groundwater potential using remote sensing: a case study in southeastern Liaoning, China
With the rise of machine learning and artificial intelligence, back propagation (BP) neural network, support vector machine (SVM), random forest model, and others can be used to predict the distribution of gro...
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Article
Application of remote sensing fuzzy assessment method in groundwater potential in Wailingding Island
To solve the problems related to the assessment of groundwater potential in small-scale areas or small arid bedrock island areas in the field of groundwater potential assessment via remote sensing technology b...
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Article
Open AccessDownregulation of ASPP2 promotes gallbladder cancer metastasis and macrophage recruitment via aPKC-ι/GLI1 pathway
Gallbladder cancer (GBC) is a highly malignant bile duct cancer with poor prognosis due to early invasion and metastasis. However, the molecular mechanisms through which GBC cells interact with the tumor micro...
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Article
Oxidative stress and histopathological alterations in liver of Cyprinus carpio L. induced by intraperitoneal injection of microcystin-LR
Microcystins (MCs) are a group of cyclic heptapeptide hepatotoxic peptides produced by cyanobacteria. Microcystins-LR (MC-LR) can inhibit the activities of protein phosphatase type 1 and type 2A (PP1 and PP2A)...
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Article
Study on shallow groundwater information extraction technology based on multi-spectral data and spatial data
Aimed at solving the difficulties, such as low efficiency and limited exploration range encountered in finding groundwater with the traditional methods, a new method was presented by using remote sensing techn...
