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Article
Open AccessPlasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease
Risk prediction for subsequent cardiovascular events remains an unmet clinical issue in patients with coronary artery disease. We aimed to investigate prognostic metabolic biomarkers by considering both shared...
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Article
Open AccessCost-effectiveness of immune checkpoint inhibitors as a first-line therapy for advanced hepatocellular carcinoma: a systematic review
Since 2017, immune checkpoint inhibitors (ICIs) have been available for the treatment of advanced hepatocellular carcinoma (HCC) or unresectable HCC, but their adoption into national medical insurance programs...
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Article
Open AccessResearch progresses of nanomaterials as lubricant additives
Friction and wear are unavoidable in mechanical movement. The use of lubricants with nano-additives can effectively reduce friction and wear, which is of great significance to saving energy and protecting the ...
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Article
Open AccessComprehensive Study on Shape Representation Methods for Shape-Based Object Recognition
This study presents a thorough analysis of shape representation techniques. Furthermore, a taxonomy of strategies for form representation and description is provided. This study aims to review the current achi...
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Article
Predictors of amputation in patients with diabetic foot ulcers: a multi-centre retrospective cohort study
Investigating risk factors for amputation in patients with diabetic foot ulcer (DFU) and develo** a nomogram prediction model.
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Article
Open AccessApplication of slow-controlled release fertilizer coordinates the carbon flow in carbon-nitrogen metabolism to effect rice quality
Slow-controlled release fertilizers are experiencing a popularity in rice cultivation due to their effectiveness in yield and quality with low environmental costs. However, the underlying mechanism by which th...
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Article
Quick-scanning X-ray absorption fine structure beamline at SSRF
The layout and characteristics of the hard X-ray spectroscopy beamline (BL11B) at the Shanghai synchrotron radiation facility are described herein. BL11B is a bending-magnet beamline dedicated to conventional ...
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Article
Machining accuracy prediction and adaptive compensation method of CNC machine tool under absence of machining process sensing
Spindle axial error is the main factor restricting machining accuracy improvements of machine tools. Monitoring the machining process of computer numerical control (CNC) machine tools is challenging due to ina...
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Article
Yersinia infection induces glucose depletion and AMPK-dependent inhibition of pyroptosis in mice
Nutritional status and pyroptosis are important for host defence against infections. However, the molecular link that integrates nutrient sensing into pyroptosis during microbial infection is unclear. Here, us...
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Open AccessInvestigation of the microfracture and damage characteristics of dam during impoundment at Sanhekou hydropower station
Dam stability is one of the most important issues in hydraulic engineering. Microfractures and damage commonly occur during impoundment, which might lead to serious dam problems. In this study, based on the en...
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Open AccessTranscriptome and metabolome analysis revealed the dynamic change of bioactive compounds of Fructus Ligustri Lucidi
The Fructus Ligustri Lucidi, the fruit of Ligustrum lucidum, contains a variety of bioactive compounds, such as flavonoids, triterpenoids, and secoiridoids. The proportions of these compounds vary greatly during ...
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Article
Effects of Testosterone in Mediating the Relationship Between Daytime Nap** and Osteoporosis in European Populations: A Mendelian Randomization Study
We aimed to explore the causal effect of daytime nap** on the risk of osteoporosis and the mediation role of testosterone in explaining this relationship. Summary data for Mendelian randomization (MR) analys...
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Article
A task allocation schema based on response time optimization in cloud computing
Task scheduling is the core research content of cloud computing. It studies how to allocate tasks between computing nodes, so that tasks are evenly allocated or the execution cost of each task is minimized or ...
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Article
Effect of Annealing Temperature on the Microstructure, Mechanical Properties and Fracture Behavior of AISI 304 Foils
In the current work, the effect of annealing temperature on the microstructure, mechanical behavior and fracture mechanism of AISI 304 foils were analyzed by a series of electron back-scatter diffraction tests...
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Article
Open AccessAI for interpreting screening mammograms: implications for missed cancer in double reading practices and challenging-to-locate lesions
Although the value of adding AI as a surrogate second reader in various scenarios has been investigated, it is unknown whether implementing an AI tool within double reading practice would capture additional su...
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Article
Open AccessA DNA demethylase reduces seed size by decreasing the DNA methylation of AT-rich transposable elements in soybean
Understanding how to increase soybean yield is crucial for global food security. The genetic and epigenetic factors influencing seed size, a major crop yield determinant, are not fully understood. We explore t...
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Biochemical characterization of a novel β-galactosidase from Pedobacter sp. with strong transglycosylation activity at low lactose concentration
A novel β-galactosidase gene (PbBgal35A) from Pedobacter sp. CAUYN2 was cloned and expressed in Escherichia coli. The gene had an open reading frame of 1917 bp, encoding 638 amino acids with a predicted molecular...
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Article
Open AccessMonosymmetric Fe-N4 sites enabling durable proton exchange membrane fuel cell cathode by chemical vapor modification
The limited durability of metal-nitrogen-carbon electrocatalysts severely restricts their applicability for the oxygen reduction reaction in proton exchange membrane fuel cells. In this study, we employ the ch...
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Article
Liquid Phase Diffusion Analysis of WC–Co–Ni–Fe/HSS Composite Materials Based on DICTRA
Thermo-Calc and DICTRA software simulations were used to predict the feasibility of Co–Ni–Fe additives applied to WC/HSS composites, and WC–Co–Ni–Fe/HSS composites were prepared. The elemental diffusion behavi...
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Article
Open AccessImproved shape-from-template method with perspective space constraints for disappearing features
Inferring the 3D surface shape of a known template from 2D images captured by a monocular camera is a challenging problem. Due to the severely underconstrained nature of the problem, inferring shape accurately...
