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Article
A real-time simulation model of water quality with the impact of internal pollution for water source reservoir
The water source reservoirs are the important urban water source in northern China. Although external pollution has been greatly improved, the internal pollutants in reservoirs continue to accumulate with the ...
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Article
Open AccessCritical role of slags in pitting corrosion of additively manufactured stainless steel in simulated seawater
Pitting corrosion in seawater is one of the most difficult forms of corrosion to identify and control. A workhorse material for marine applications, 316L stainless steel (316L SS) is known to balance resistanc...
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Article
A prognostic gene signature for gastric cancer and the immune infiltration-associated mechanism underlying the signature gene, PLG
Globally, gastric cancer (GC) is a common and lethal solid malignant tumor. Identifying the molecular signature and its functions can provide mechanistic insights into GC development and new methods for target...
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Article
Cucurbit[8]uril-mediated multi-color fluorescence system for time-dependent information encryption
Programming microscopic assembly mode to control macroscopic property is an attractive research objective. In particular, controlling molecular assembly to control fluorescence is of considerable interest for ...
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Article
Open AccessCorrection to: A Computational Platform Integrating a Mechanistic Model of Crohn’s Disease for Predicting Temporal Progression of Mucosal Damage and Healing
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Article
Spatial changes and driving factors of lake water quality in Inner Mongolia, China
Lakes play important roles in sustaining the ecosystem and economic development in Inner Mongolia Autonomous Region of China, but the spatial patterns and driving mechanisms of water quality in lakes so far re...
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Article
Significant diurnal variation of CO2 flux from a shallow eutrophic lake: effects of submerged aquatic vegetation and algae bloom
Shallow eutrophic lake with submerged aquatic vegetation (SAV) has high primary productivity, but its diurnal variation of CO2 flux remains unclear. Moreover, algae bloom has become a serious environmental proble...
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Article
Open AccessA Computational Platform Integrating a Mechanistic Model of Crohn’s Disease for Predicting Temporal Progression of Mucosal Damage and Healing
Physicians are often required to make treatment decisions for patients with Crohn’s disease on the basis of limited objective information about the state of the patient’s gastrointestinal tissue while aiming t...
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Article
3D printing of metal-based materials for renewable energy applications
Large-scale renewable energy must overcome conversion and storage challenges before it can replace fossil fuels due to its intermittent nature. However, current sustainable energy devices still suffer from hig...
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Article
Open AccessNanoporous gold nanoleaf as tunable metamaterial
We have studied optical properties of single-layer and multi-fold nanoporous gold leaf (NPGL) metamaterials and observed highly unusual transmission spectra composed of two well-resolved peaks. We explain this...
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Article
Evaluation of anemia, malnutrition, mineral, and bone disorder for maintenance hemodialysis patients based on bioelectrical impedance vector analysis (BIVA)
ESRD (End-stage renal disease) treatment is a comprehensive medical process and requires numerous serological biochemical tests (SBTs) in diagnosis. To reduce these invasive, expensive, cumbersome, and time-co...
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Article
Tongue color clustering and visual application based on 2D information
Studies have shown the association between tongue color and diseases. To help clinicians make more objective and accurate decisions quickly, we take unsupervised learning to deal with the basic clustering of ...
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Chapter and Conference Paper
Effect of Alumina Ceramics Surface Condition on the Wetting of Liquid Lead
The effect of alumina ceramics on the characteristics of liquid was investigated by the sessile drop method. The surface 3D appearance and of the alumina substrate were measured by confocal laser scann...
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Protocol
Efficient Culture of Intestinal Organoids with Blebbistatin
The intestinal epithelium is one of the most rapidly self-renewing tissues throughout life in mammals. A small population of stem cells at the base of crypt in the epithelium can continually self-renew and giv...
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Article
Open AccessA growth factor-free culture system underscores the coordination between Wnt and BMP signaling in Lgr5+ intestinal stem cell maintenance
Lgr5+ intestinal stem cells (ISCs) drive the fast renewal of intestinal epithelium. Several signaling pathways have been shown to regulate ISC fates. However, it is unclear what are the essential signals to susta...
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Article
Open AccessMonolayer culture of intestinal epithelium sustains Lgr5+ intestinal stem cells
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Article
NiAu Single Atom Alloys for the Non-oxidative Dehydrogenation of Ethanol to Acetaldehyde and Hydrogen
Gold is examined here as an alternative to copper for the selective dehydrogenation of ethanol to acetaldehyde and hydrogen. Despite its high selectivity, gold is only active at temperatures higher than 250 °C...
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Article
Directed accumulation of less toxic pimaricin derivatives by improving the efficiency of a polyketide synthase dehydratase domain
Pimaricin is an important polyene antifungal antibiotic that binds ergosterol and extracts it from fungal membranes. In previous work, two pimaricin derivatives (1 and 2) with improved pharmacological activities ...
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Article
Open AccessBMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes
The intestinal epithelium possesses a remarkable self-renewal ability, which is mediated by actively proliferating Lgr5+ stem cells. Bone morphogenetic protein (BMP) signalling represents one major counterforce t...
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Article
Engineered biosynthesis of pimaricin derivatives with improved antifungal activity and reduced cytotoxicity
Pimaricin is an important antifungal antibiotic for antifungal therapy and prevention of mould contamination in the food industry. In this study, three new pimaricin derivatives, 12-decarboxy-12-methyl pimaric...
