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Article
Open AccessSystematic single-cell analysis reveals dynamic control of transposable element activity orchestrating the endothelial-to-hematopoietic transition
The endothelial-to-hematopoietic transition (EHT) process during definitive hematopoiesis is highly conserved in vertebrates. Stage-specific expression of transposable elements (TEs) has been detected during z...
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Article
Open AccessHALD, a human aging and longevity knowledge graph for precision gerontology and geroscience analyses
Human aging is a natural and inevitable biological process that leads to an increased risk of aging-related diseases. Develo** anti-aging therapies for aging-related diseases requires a comprehensive underst...
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Article
Open AccessA machine learning-based data mining in medical examination data: a biological features-based biological age prediction model
Biological age (BA) has been recognized as a more accurate indicator of aging than chronological age (CA). However, the current limitations include: insufficient attention to the incompleteness of medical data...
