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Chapter
Force-Dependent Remodeling of Cell-to-Cell Adhesion Through the Regulation of Phase Separation
During development and regeneration, cells vigorously migrate to achieve morphogenesis of tissues and organs. Upon these dynamic processes, cells are exposed to various forces such as compression force, stretc...
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Article
Open AccessRole of miR-182/PDCD4 axis in aggressive behavior of prostate cancer in the African Americans
Prostate cancer is one of the most commonly diagnosed cancers among men. African Americans (AA) are at an increased risk of develo** prostate cancer compared to European Americans (EA). miRNAs play a critica...
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Article
Open AccessProtrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning
Protrudin is a protein that resides in the membrane of the endoplasmic reticulum and is highly expressed in the nervous system. Although mutations in the human protrudin gene (ZFYVE27, also known as SPG33) give r...
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Article
Open AccessLncRNA CDKN2B-AS1/miR-141/cyclin D network regulates tumor progression and metastasis of renal cell carcinoma
The molecular heterogeneity of renal cell carcinoma (RCC) complicates the therapeutic interventions for advanced metastatic disease and thus its management remains a significant challenge. This study investiga...
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Article
Open AccessTemporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection
The co-evolution and co-existence of viral pathogens with their hosts for millions of years is reflected in dynamic virus-host protein-protein interactions (PPIs) that are intrinsic to the spread of infections...
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Chapter
Contribution of Mass Spectrometry-Based Proteomics to Discoveries in Developmental Biology
Understanding multicellular organism development from a molecular perspective is no small feat, yet this level of comprehension affords clinician-scientists the ability to identify root causes and mechanisms o...
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Article
A novel microRNA regulator of prostate cancer epithelial–mesenchymal transition
The most frequent alteration in the prostate oncogenome is loss of chromosome (chr) 8p21 that has been associated with loss of NKX3.1 homeobox gene. Chr8p21 deletions increase significantly with tumor grade an...
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Article
Improvement of the Thermoelectric Properties of the Chimney-Ladder Compounds in the Ru-Mn-Si System
Directionally solidified alloys in the Ru-Mn-Si system exhibit a particular microstructure including columnar compositional variation due to the formation of many different chimney-ladder phases along the grow...
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Article
New method to control defect reaction induced by electron-hole recombination for long-living widegap light-emitting devices
A new artificial defect-control technique for reducing the electron-hole recombination times at an electrically active center in order to improve the lifetime of widegap light-emitting diodes is presented. It ...
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Article
Molecular cloning and cytochemical analysis of exopolygalacturonase from carrot
Exopolygalacturonase (exo-PGase, EC 3.2.1.67) attacks the non-reducing terminus of the polygalacturonic acid in pectic molecules, releasing galacturonic acid. We cloned the cDNA of exo-P...
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Article
Polymerization of Ring-Substituted Phenylalanine N-Carboxyanhydride by Poly(2-vinylpyridine)
Polymerizations of a series of phenylalanine NCA’s carrying various ring substituents, such as P-CH3O, P-H, P-NO2, and m-NO2, initiated by poly(2-vinylpyridine) were investigated in different solvents, such as di...
