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Article
Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis
Current regulatory guidelines on drug-food interactions recommend an early assessment of food effect to inform clinical dosing instructions, as well as a pivotal food effect study on the to-be-marketed formula...
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Article
Interventions Designed to Improve HIV Continuum of Care Outcomes for Persons with HIV in Contact with the Carceral System in the USA
To describe existing evidence and identify future directions for intervention research related to improving HIV care outcomes for persons with HIV involved in the carceral system in the USA, a population with ...
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Isolation, biochemical characterization, and development of a biodegradable antimicrobial film from Cirrhinus mrigala scale collagen
Collagen is a promising candidate for food and pharmaceutical applications due to its excellent biocompatibility, low antigenicity, and controlled biodegradability; however, its heavy price restricts its utili...
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Article
Open AccessRole of miR-182/PDCD4 axis in aggressive behavior of prostate cancer in the African Americans
Prostate cancer is one of the most commonly diagnosed cancers among men. African Americans (AA) are at an increased risk of develo** prostate cancer compared to European Americans (EA). miRNAs play a critica...
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Article
Correction to: Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective
An Erratum to this paper has been published: https://doi.org/10.1208/s12248-020-00535-z
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Article
Open AccessUse of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspective
The effect of food on pharmacokinetic properties of drugs is a commonly observed occurrence affecting about 40% of orally administered drugs. Within the pharmaceutical industry, significant resources are inves...
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Article
Open AccessLncRNA CDKN2B-AS1/miR-141/cyclin D network regulates tumor progression and metastasis of renal cell carcinoma
The molecular heterogeneity of renal cell carcinoma (RCC) complicates the therapeutic interventions for advanced metastatic disease and thus its management remains a significant challenge. This study investiga...
