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  1. No Access

    Article

    Synthesis and cytotoxic activity of genistein derivatives

    A series of genistein derivatives was prepared and tested in vitro against leukocythemia (HL-60), colorectal adenocarcinoma (HT-29), and human gastric adenocarcinoma (SGC-7901) cell lines. Among these derivati...

    **ng Zheng, Xu Yao, Yunmei Liu, Zitong Zheng, Jianguo Cao… in Medicinal Chemistry Research (2010)

  2. No Access

    Article

    Synthetic derivatives of chrysin and their biological activities

    Chrysin is one of flavones constituents of Orocylumineicum vent. It has been a hot spot as a potential chemopreventive agent and as a natural molecule with numerous biological activities such as antioxidant, anti...

    Yunmei Liu, **udao Song, Jun He, **ng Zheng, Houlv Wu in Medicinal Chemistry Research (2014)

  3. No Access

    Article

    Synthesis of new 7-O-modified chrysin derivatives and their anti-proliferative and apoptotic effects on human gastric carcinoma MGC-803 cells

    Two series of 7-O-modified chrysin derivatives were prepared from 7-O-carboxymethyl chrysin(2a), 7-O-carboxypropylchrysin(2b) and short-chain alcohols by using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydroc...

    Yunmei Liu, **udao Song, ** Ma, Jun He… in Chemical Research in Chinese Universities (2014)

  4. No Access

    Article

    Synthesis of novel amino acid derivatives containing chrysin as anti-tumor agents against human gastric carcinoma MGC-803 cells

    Two series of amino acid derivatives containing chrysin were prepared from 7-O-carboxymethyl chrysin (4a) and 7-O-carboxypropyl chrysin (4b) and amino acid methyl esters by treatment with 1-ethyl-3-(3-dimethylami...

    **udao Song, Yunmei Liu, ** Ma, Jun He, **ng Zheng… in Medicinal Chemistry Research (2015)

  5. Chapter

    Considering Severity of Safety-Critical System Outcomes in Risk Analysis: An Extension of Fault Tree Analysis

    With the advent of digitalisation and big data sources, new advanced tools are needed to precisely project safety-critical system outcomes. Existing systems safety analysis methods, such as fault tree analysis...

    David B. Kaber, Yunmei Liu, Mei Lau in Safety in the Digital Age (2023)

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  6. No Access

    Article

    3D quantitative structure–activity relationships study on anti-gastric cancer of chrysin derivatives

    In this paper, 3D-QSAR models were constructed to conduct a preliminary study on the structure–activity relationship of chrysin. The three-dimensional structures of the selected 54 chrysin derivatives were con...

    Yunmei Liu, Zejie Tian, Hui Li, Zhenhua Liu, Lei Shi… in Journal of Mathematical Chemistry (2023)

  7. No Access

    Article

    Consequence severity-probability importance measure for fault tree analysis

    Fault Tree Analysis (FTA) has realized substantial application for safety engineering; however, the method is not without limitations. Traditional FTA requires substantial time and effort, even for single faul...

    Mei Y. Lau, Yunmei Liu, David B. Kaber in International Journal of System Assurance … (2024)