![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Consequence severity-probability importance measure for fault tree analysis
Fault Tree Analysis (FTA) has realized substantial application for safety engineering; however, the method is not without limitations. Traditional FTA requires substantial time and effort, even for single faul...
-
Article
3D quantitative structure–activity relationships study on anti-gastric cancer of chrysin derivatives
In this paper, 3D-QSAR models were constructed to conduct a preliminary study on the structure–activity relationship of chrysin. The three-dimensional structures of the selected 54 chrysin derivatives were con...
-
Chapter
Considering Severity of Safety-Critical System Outcomes in Risk Analysis: An Extension of Fault Tree Analysis
With the advent of digitalisation and big data sources, new advanced tools are needed to precisely project safety-critical system outcomes. Existing systems safety analysis methods, such as fault tree analysis...
-
Article
Synthesis of novel amino acid derivatives containing chrysin as anti-tumor agents against human gastric carcinoma MGC-803 cells
Two series of amino acid derivatives containing chrysin were prepared from 7-O-carboxymethyl chrysin (4a) and 7-O-carboxypropyl chrysin (4b) and amino acid methyl esters by treatment with 1-ethyl-3-(3-dimethylami...
-
Article
Synthesis of new 7-O-modified chrysin derivatives and their anti-proliferative and apoptotic effects on human gastric carcinoma MGC-803 cells
Two series of 7-O-modified chrysin derivatives were prepared from 7-O-carboxymethyl chrysin(2a), 7-O-carboxypropylchrysin(2b) and short-chain alcohols by using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydroc...
-
Article
Synthetic derivatives of chrysin and their biological activities
Chrysin is one of flavones constituents of Orocylumineicum vent. It has been a hot spot as a potential chemopreventive agent and as a natural molecule with numerous biological activities such as antioxidant, anti...
-
Article
Synthesis and cytotoxic activity of genistein derivatives
A series of genistein derivatives was prepared and tested in vitro against leukocythemia (HL-60), colorectal adenocarcinoma (HT-29), and human gastric adenocarcinoma (SGC-7901) cell lines. Among these derivati...