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    Article

    Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer’s Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways

    Patients with Alzheimer's disease have increased risk of develo** heart disease, which therefore highlights the need for strategies aiming at reducing Alzheimer's disease-related cardiovascular disease. Foli...

    Da-Tong Ju, Rwei-Fen S. Huang, Bruce Chi-Kang Tsai, Yi-Chen Su in Neurotoxicity Research (2023)

  2. Article

    Open Access

    Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration

    It is known that the medicinal herb Alpinia oxyphylla Miq. is widely used as a remedy for diarrhea as well as the symptoms accompanying hypertension and cerebrovascular disorders. Moreover, it has also been re...

    Yung-Ming Chang, Hen-Hong Chang in BMC Complementary and Alternative Medicine (2017)

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    Article

    Distribution and double generating function of number of patterns in a sequence of Markov dependent multistate trials

    In this manuscript, the dual relationship between the probability of number of runs and patterns and the probability of waiting time of runs and patterns in a sequence of multistate trials has been studied via...

    Yung-Ming Chang, James C. Fu, Han-Ying Lin in Annals of the Institute of Statistical Mat… (2012)

  4. Article

    Open Access

    Genetic copy number variants in myocardial infarction patients with hyperlipidemia

    Cardiovascular disease is the chief cause of death in Taiwan and many countries, of which myocardial infarction (MI) is the most serious condition. Hyperlipidemia appears to be a significant cause of myocardia...

    Wei-Chung Shia, Tien-Hsiung Ku, Yu-Ming Tsao, Chien-Hsun Hsia in BMC Genomics (2011)

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    Article

    On Average Run Lengths of Control Charts for Autocorrelated Processes

    It is well known that statistical control charts such as Shewhart, CUSUM and EWMA charts have widespread applications in improving the quality for manufacturing and service systems. The average run length is a...

    Yung-Ming Chang, Tung-Lung Wu in Methodology and Computing in Applied Probability (2011)

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    Chapter

    Earthworms: A Potent Herbal Target for TCM (CAM) Research

    Earthworms, also known as Dilong, have been widely used in traditional Chinese medicine for thousands of years. The medicinal applications of earthworms in various remedies included blood stagnation removal, w...

    Yung-Ming Chang, Wei-Yi Chi, Edwin L. Cooper, Wei-Wen Kuo in Biology of Earthworms (2011)