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Open AccessGeneration of clinical-grade human induced pluripotent stem cells in Xeno-free conditions
Human induced pluripotent stem cells (hiPSCs) are considered as one of the most promising seed cell sources in regenerative medicine. Now hiPSC-based clinical trials are underway. To ensure clinical safety, ce...
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Open AccessEfficient generation of mouse ESCs-like pig induced pluripotent stem cells
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Tbx3 and Nr5α2 Play Important Roles in Pig Pluripotent Stem Cells
Pigs are valuable animal models in pre-clinical research due to their anatomical and similarity to human-beings. Little is known about porcine embryonic development and porcine pluripotent stem cells. Recently...
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Open AccessDerivation of androgenetic embryonic stem cells from m-carboxycinnamic acid bishydroxamide (CBHA) treated androgenetic embryos
The androgenetic embyronic stem (aES) cells are useful models in studying the effects of imprinted genes on pluripotency maintaining and embryo development. The expression patterns of imprinted genes are signi...