17 Result(s)

Article

Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression

Metastasis predicts poor prognosis in cancer patients. It has been recognized that specific tumor microenvironment defines cancer cell metastasis, whereas the underlying mechanisms remain elusive. Here we show...

Jianbo An, Yushi Nagaki, Satoru Motoyama, Yuta Kuze, Midori Hoshizaki… in Oncogene (2022)

Article

Hydride-ion-conducting K₂NiF₄-type Ba–Li oxyhydride solid electrolyte

Hydrogen transport in solids, applied in electrochemical devices such as fuel cells and electrolysis cells, is key to sustainable energy societies. Although using proton (H⁺) conductors is an attractive choice, p...

Fumitaka Takeiri, Akihiro Watanabe, Kei Okamoto, Dominic Bresser… in Nature Materials (2022)

Article

Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection

Crosstalk between the autonomic nervous system and the immune system by means of the sympathetic and parasympathetic pathways is a critical process in host defence. Activation of the sympathetic nervous system...

Seiki Fujiwara, Midori Hoshizaki, Yu Ichida, Dennis Lex… in Nature Microbiology (2019)

Article

Nationwide surveillance of bacterial respiratory pathogens conducted by the Surveillance Committee of Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Clinical Microbiology in 2009: general view of the pathogens’ antibacterial susceptibility

For the purpose of nationwide surveillance of antimicrobial susceptibility of bacterial respiratory pathogens from patients in Japan, the Japanese Society of Chemotherapy (JSC) started a survey in 2006. From 2...

Akira Watanabe, Katsunori Yanagihara… in Journal of Infection and Chemotherapy (2012)

Chapter

Ventilator-induced lung injury, cytokines, PEEP, and mortality: implications for practice and for clinical trials

A mainstay in the supportive care of patients with acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is mechanical ventilation. However, a number of animal and clinical studies have demonstrat...

Arthur S. Slutsky, Yumiko Imai in Applied Physiology in Intensive Care Medicine 2 (2012)

Article

Nationwide surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2008: general view of the pathogens’ antibacterial susceptibility

For the purpose of nationwide surveillance of the antimicrobial susceptibility of bacterial respiratory pathogens collected from patients in Japan, the Japanese Society of Chemotherapy conducted a third year o...

Yoshihito Niki, Hideaki Hanaki, Tetsuya Matsumoto… in Journal of Infection and Chemotherapy (2011)

Reference Work Entry In depth

Respiratory Syndrome, Severe Acute

Keiji Kuba, Yumiko Imai, Josef Penninger in Encyclopedia of Molecular Mechanisms of Disease (2009)

Article

Rapidly progressive fatal pneumococcal sepsis in adults: a report of two cases

We report two cases of a rapidly progressive fatal overwhelming pneumococcal infection. Patient 1 was a 67-year-old man with a 24-h history of fever and malaise and was transferred to our department. He was se...

Yasushi Iinuma, Yasuo Hirose, Toshiharu Tanaka… in Journal of Infection and Chemotherapy (2007)

Article

PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide

Platelet-activating factor (PAF) induces pulmonary edema and has a key role in acute lung injury (ALI). Here we show that PAF induces pulmonary edema through two mechanisms: acid sphingomyelinase (ASM)-depende...

Rolf Göggel, Supandi Winoto-Morbach, Gabriele Vielhaber, Yumiko Imai… in Nature Medicine (2004)