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Article
Slow TCA flux and ATP production in primary solid tumours but not metastases
Tissues derive ATP from two pathways—glycolysis and the tricarboxylic acid (TCA) cycle coupled to the electron transport chain. Most energy in mammals is produced via TCA metabolism1. In tumours, however, the abs...
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Article
Transcriptome Profiling of Duodenum Reveals the Importance of Boron Supplementation in Modulating Immune Activities in Rats
As an essential trace element, appropriate boron supplementation can promote immune function of animals. To illustrate the effects of boron in a rat model, RNA-Seq was conducted for the RNA from duodenum after...
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Article
Open AccessThe RNA-binding protein Musashi2 governs osteoblast-adipocyte lineage commitment by suppressing PPARγ signaling
Osteoporosis caused by aging is characterized by reduced bone mass and accumulated adipocytes in the bone marrow cavity. How the balance between osteoblastogenesis and adipogenesis from bone marrow mesenchymal...
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Article
Bone marrow niches in the regulation of bone metastasis
The bone marrow has been widely recognised to host a unique microenvironment that facilitates tumour colonisation. Bone metastasis frequently occurs in the late stages of malignant diseases such as breast, pro...
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Chapter and Conference Paper
Shared Component Cross Punctuation Clauses Recognition in Chinese
NT (Naming-telling) Clause Complex Framework defines the clause complex structures through component sharing and logic-semantic relationships. In this paper, we formalize component sharing recognition as a mul...
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Article
Pore Structure Evaluation of Bioclastic Limestone Using NMR and HPMI Measurements
Pore structure evaluation is a crucial segment of revealing the reservoir characteristics and percolation mechanism. Considering the diversity of origins, types and combinations in reservoir space, the effecti...
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Article
Open AccessParacrine and endocrine actions of bone—the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts
The skeleton is a dynamic organ that is constantly remodeled. Proteins secreted from bone cells, namely osteoblasts, osteocytes, and osteoclasts exert regulation on osteoblastogenesis, osteclastogenesis, and a...
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Article
Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid
Craniofacial anomalies (CFAs) characterized by birth defects of skull and facial bones are the most frequent congenital disease. Genomic analysis has identified multiple genes responsible for CFAs; however, th...