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  1. No Access

    Article

    Recurrent intestinal inflammation with a perianal abscess is not always Crohn’s disease: a patient with a complex Meckel’s diverticulum diagnosed by double-balloon endoscopy

    Recurrent intestinal inflammation and refractory perianal abscesses are typical manifestations of Crohn’s disease. However, these conditions are not always due to Crohn’s disease. A 25-year-old male with recur...

    Yuji Hiraoka, Satoshi Shinozaki, Tomonori Yano… in Clinical Journal of Gastroenterology (2020)

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    Article

    Low-field magnetoelectric effect at room temperature

    Only few magnetoelectric materials, where magnetism and ferroelectricity are coupled, are known to exist at room temperature, and in most cases the magnetoelectric coupling is weak. The discovery of strong roo...

    Yutaro Kitagawa, Yuji Hiraoka, Takashi Honda, Taishi Ishikura… in Nature Materials (2010)

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    Article

    T cell-mediated immune response enhances the severity of myocarditis in secondary cardiotropic virus infection in mice

    In this report, we showed that a previous enterovirus exposure in ordinary mice with normal T cell function, but not in T cell-deficient mice, can influence development of myocardial inflammation with a secon...

    Chiharu Kishimoto, Yuji Hiraoka, Hitoshi Takada in Basic Research in Cardiology (2001)

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    Article

    Failure of treatment with interleukin-2 receptor-specific monoclonal antibody in acute coxsackievirus B3 myocarditis in mice

    T cell activation is assumed to play a crucial role in many viral infections. An important marker for the activation of T cells is the interleukin-2 receptor (IL-2R); resting T lymphocytes do not bear detectab...

    Chiharu Kishimoto, Yuji Hiraoka, Hitoshi Takada, Masahiko Kurokawa… in Heart and Vessels (1997)

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    Article

    Effects of levamisole, an immunomodulator, upon murine encephalomyocarditis virus myocarditis

    To test the therapeutic efficacy of levamisole, 5-week-old DBA/2 mice were inoculated intraperitoneally with 10 plaque-forming units of encephalomyocarditis virus. Levamisole (2.5mg/kg/per day) was administere...

    Chiharu Kishimoto, Hitoshi Takada, Yuji Hiraoka, Masahiko Kurokawa… in Heart and Vessels (1997)

  6. No Access

    Article

    The effects of lobenzarit disodium, a novel immunomodulator, upon murine coxsackievirus B3 myocarditis

    The aim of this study is to test the therapeutic efficacy of immunomodulation with lobenzarit disodium (CCA) upon coxsackievirus B3 (CB3) myocarditis. Two-week-old C3H/He mice were inoculated with 103 plaque-form...

    Hitoshi Takada, Chiharu Kishimoto, Yoshito Kuroki, Isao Matsushita… in Heart and Vessels (1993)