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Article
Who benefits from hormone therapy?
Not all hormone receptor (HR)-positive tumors respond to hormone therapy, although hormone therapy has brought significant benefits to breast cancer patients. In order to improve the efficacy of hormone therap...
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Article
Analysis of ipsilateral breast tumor recurrences after breast-conserving treatment based on the classification of true recurrences and new primary tumors
Ipsilateral breast tumor recurrences (IBTR) after breast-conserving treatment include two different entities: true recurrence (TR) thought to occur when residual cancer cells grow gradually to detectable size ...
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Article
Long-term suppression of lymphangitic lung metastasis from breast cancer using biweekly docetaxel: A case report
A 45-year-old woman underwent a modified radical mastectomy for right breast cancer in July 1996. As lymph node metastases were quite advanced, chemotherapy was started with anthracyclines. Four years after su...
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Article
Phase I study of docetaxel and cyclophosphamide in patients with advanced or recurrent breast cancer
A phase I clinical study of combination chemotherapy with docetaxel and cyclophosphamide (CPA) was performed to determine the maximum tolerated dose (MTD), the incidence and severity of toxicities and the phar...
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Article
Recurrence of Breast Cancer following local excision alone for ductal carcinoma in situ
To assess recurrence of breast cancer following local excision alone for ductal carcinoma in situ.
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Article
Atypical cystic lobule of the breast: An early stage of low-grade ductal carcinomain-situ
The authors describe the characteristics of atypical cystic lobules (ACLs), which represent a step in the formation of low-grade ductal carcinomain-situ. The authors define ACLs as a proliferation of luminal cell...
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Article
Trends of IL-6 and IL-8 levels in patients with recurrent breast cancer: preliminary report
We reported that IL-6 and IL-8 levels at the beginning of treatment are predictive indicators of response to therapy and prognosis of patients with recurrent breast cancer. The aim of this study was to investi...
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Article
A case report of advanced male breast cancer with an objective response to tamoxifen treatment
A 70-year-old man presented with a firm tumor in his right breast first noticed eight years ago. The tumor had enlarged gradually and had produced an ulcer with bleeding. On physical examination, a huge tumor ...
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Article
Sudden hemorrhage of the breast caused by breast cancer: a case report and review of the literature
A rare case of sudden hemorrhage caused by breast cancer is reported. A 71-year-old woman noted bleeding from her left breast. Physical examination of the left breast showed a localized open cavity accompanied...
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Article
Current status and controversial issues concerning endocrine therapy for patients with recurrent breast cancer in Japan
Four different endocrine therapeutic agents have been used in Japan since 1996. However, a consensus regarding proper use of these agents has not yet been established. Therefore, a questionaire survey of Japan...
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Article
Granular cell tumor of the breast diagnosed by core needle biopsy: a case report
Granular cell tumor rarely occurs in the breast. We report a 69-year-old woman with a right breast mass that simulated carcinoma on palpation, mammography, and ultrasonography. Aspiration biopsy cytology showe...
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Article
Chemoendocrine therapy: Basic science and clinical aspects