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Granular cell tumor of the breast diagnosed by core needle biopsy: a case report

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Abstract

Granular cell tumor rarely occurs in the breast. We report a 69-year-old woman with a right breast mass that simulated carcinoma on palpation, mammography, and ultrasonography. Aspiration biopsy cytology showed no malignant atypical cells. Core needle biopsy was performed to obtain an accurate diagnosis. The lesion was histologically confirmed to be a granular cell tumor. Immunostaining was positive for S-100 protein and vimentin, and negative for keratin, carcinoembryonic antigen, estrogen receptor and gross cystic disease fluid protein-15. The tumor was treated by wide local excision. Surgeons should be aware that granular cell tumor can resemble breast cancer in order to avoid performing a needless radical mastectomy.

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Abbreviations

GCDP-15:

Gross cystic disease fluid protein-15

GCTB:

Granular cell tumor of the breast

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Authors and Affiliations

  1. Second Department of Surgery, Gunma University School of Medicine, Japan

    Jun Horiguchi, Hiroyuki Takei, Michio Maemura, Yukio Koibuchi, Yoshio Horii & Yasuo Morishita

  2. Department of Emergency and Critical Care Medicine, Gunma University School of Medicine, Japan

    Yuichi lino & Takao Yokoe

  3. Second Department of Pathology, Gunma University School of Medicine, Japan

    Tetsunari Oyama, Toshiaki Hikino & Takashi Nakajima

Authors
  1. Jun Horiguchi
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  2. Yuichi lino
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  3. Hiroyuki Takei
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  4. Michio Maemura
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  5. Yukio Koibuchi
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  6. Yoshio Horii
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  7. Takao Yokoe
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  8. Tetsunari Oyama
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  9. Toshiaki Hikino
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  10. Takashi Nakajima
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  11. Yasuo Morishita
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Horiguchi, J., lino, Y., Takei, H. et al. Granular cell tumor of the breast diagnosed by core needle biopsy: a case report. Breast Cancer 6, 69–71 (1999). https://doi.org/10.1007/BF02966910

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  • DOI: https://doi.org/10.1007/BF02966910

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