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Open AccessEight-lncRNA signature of cervical cancer were identified by integrating DNA methylation, copy number variation and transcriptome data
Copy number variation (CNV) suggests genetic changes in malignant tumors. Abnormal expressions of long non-coding RNAs (lncRNAs) resulted from genomic and epigenetic abnormalities play a driving role in tumori...
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Local injection of a single dose of simvastatin augments osteoporotic bone mass in ovariectomized rats
The aim of this study was to evaluate the effects and explore the mechanism of a local injection of a single dose of simvastatin as a strategy to strengthen target bone. Simvastatin was injected into the femur...