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Open AccessStructural insights into the covalent regulation of PAPP-A activity by proMBP and STC2
Originally discovered in the circulation of pregnant women as a protein secreted by placental trophoblasts, the metalloprotease pregnancy-associated plasma protein A (PAPP-A) is also widely expressed by many o...
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Open AccessEight-lncRNA signature of cervical cancer were identified by integrating DNA methylation, copy number variation and transcriptome data
Copy number variation (CNV) suggests genetic changes in malignant tumors. Abnormal expressions of long non-coding RNAs (lncRNAs) resulted from genomic and epigenetic abnormalities play a driving role in tumori...