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  1. Article

    Open Access

    Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state

    PPM1D encodes a serine/threonine phosphatase that regulates numerous pathways including the DNA damage response and p53. Activating mutations and amplification of PPM1D are found across numerous cancer types. GSK...

    Peter G. Miller, Murugappan Sathappa, Jamie A. Moroco, Wei Jiang in Nature Communications (2022)

  2. Article

    Open Access

    Publisher Correction: A Fast and Refined Cancer Regions Segmentation Framework in Whole-slide Breast Pathological Images

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Zichao Guo, Hong Liu, Haomiao Ni, **angdong Wang, Mingming Su in Scientific Reports (2020)

  3. Article

    Open Access

    G-protein signaling is required for increasing germline stem cell division frequency in response to mating in Drosophila males

    Adult stem cells divide to renew the stem cell pool and replenish specialized cells that are lost due to death or usage. However, little is known about the mechanisms regulating how stem cells adjust to a dema...

    Manashree S. Malpe, Leon F. McSwain, Karl Kudyba, Chun L. Ng in Scientific Reports (2020)

  4. Article

    Open Access

    A Fast and Refined Cancer Regions Segmentation Framework in Whole-slide Breast Pathological Images

    Supervised learning methods are commonly applied in medical image analysis. However, the success of these approaches is highly dependent on the availability of large manually detailed annotated dataset. Thus a...

    Zichao Guo, Hong Liu, Haomiao Ni, **angdong Wang, Mingming Su in Scientific Reports (2019)

  5. Article

    Open Access

    Haze smoke impacts survival and development of butterflies

    The Southeast Asian transboundary haze contains a mixture of gases and particles from forest fires and negatively impacts people’s health and local economies. However, the effect of the haze on organisms other...

    Yue Qian Tan, Emilie Dion, Antónia Monteiro in Scientific Reports (2018)

  6. Article

    Open Access

    Enhanced Defluoridation Using Novel Millisphere Nanocomposite of La-Doped Li-Al Layered Double Hydroxides Supported by Polymeric Anion Exchanger

    A novel nanocomposite bead LaLiAl-LDH@201 was fabricated by do** a small amount of La into nanocrystalline Li/Al layered double hydroxides (LDHs) pre-confined inside polystyrene anion exchanger D201 (LiAl-LD...

    Jianguo Cai, Yanyang Zhang, Yue Qian, Chao Shan, Bingcai Pan in Scientific Reports (2018)

  7. Article

    Open Access

    Association of Homocysteine with Aysmptomatic Intracranial and Extracranial Arterial Stenosis in Hypertension Patients

    Elevated plasma homocysteine (Hcy) is suggested as an independent risk factor for stroke. We aimed to investigate the association of Hcy concentration with intracranial atherosclerosis (ICAS) and extracranial ...

    Yan Wang, ** Zhang, Yuesheng Qian, **aofeng Tang, Huawei Ling in Scientific Reports (2018)

  8. Article

    Open Access

    Association of Inter-arm Blood Pressure Difference with Asymptomatic Intracranial and Extracranial Arterial Stenosis in Hypertension Patients

    Inter-arm blood pressure (BP) difference has been associated with ischemic stroke. Local atherosclerosis of stroke differ among vulnerable individuals, whereas intracranial arterial stenosis (ICAS) is more fre...

    Yan Wang, ** Zhang, Yuesheng Qian, **aofeng Tang, Huawei Ling in Scientific Reports (2016)