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Article
General synthesis of transition metal nitride arrays by ultrafast flash joule heating within 500 ms
Transition metal nitrides (TMNs) are considered as viable alternatives to noble metal catalysts owing to their versatile electronic structure and favorable catalytic performance. However, the conventional synt...
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Article
Open AccessLncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression
Non-coding RNAs are responsible for oncogenesis and the development of stemness features, including multidrug resistance and metastasis, in various cancers. Expression of lncRNA MIR31HG in lung cancer tissues ...
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Article
Open AccessProteomic characterization of esophageal squamous cell carcinoma response to immunotherapy reveals potential therapeutic strategy and predictive biomarkers
Immunotherapy is the first-line therapy for esophageal squamous cell carcinoma (ESCC), yet many patients do not respond due to drug resistance and the lack of reliable predictive markers. We collected 73 ESCC ...
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Article
EGFR and ERBB2 Exon 20 Insertion Mutations in Chinese Non-small Cell Lung Cancer Patients: Pathological and Molecular Characterization, and First-Line Systemic Treatment Evaluation
Data from studies looking at both EGFR and ERBB2 exon 20 insertion mutations (-20ins) in the same cohort of patients with non-small cell lung cancer (NSCLC) are limited.
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Article
Open AccessCorrection: Single-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma
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Article
Open AccessNew dienelactone hydrolase from microalgae bacterial community-Antibiofilm activity against fish pathogens and potential applications for aquaculture
Biofilms are resistant to many traditional antibiotics, which has led to search for new antimicrobials from different and unique sources. To harness the potential of aquatic microbial resources, we analyzed th...
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Article
A Hubbard exciton fluid in a photo-doped antiferromagnetic Mott insulator
The undoped antiferromagnetic Mott insulator naturally has one charge carrier per lattice site. When it is doped with additional carriers, they are unstable to spin-fluctuation-mediated Cooper pairing as well ...
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Article
Open AccessNovel marine metalloprotease—new approaches for inhibition of biofilm formation of Stenotrophomonas maltophilia
Many marine organisms produce bioactive molecules with unique characteristics to survive in their ecological niches. These enzymes can be applied in biotechnological processes and in the medical sector to repl...
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Article
Open AccessClonal dynamics and Stereo-seq resolve origin and phenotypic plasticity of adenosquamous carcinoma
The genomic origin and development of the biphasic lung adenosquamous carcinoma (ASC) remain inconclusive. Here, we derived potential evolutionary trajectory of ASC through whole-exome sequencing, Stereo-seq, ...
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Article
Open AccessSingle-cell profiling reveals the trajectory of FOLR2-expressing tumor-associated macrophages to regulatory T cells in the progression of lung adenocarcinoma
An immunosuppressive microenvironment enriched with regulatory CD4+ T lymphocytes (Tregs) facilitates the progression of lung adenocarcinoma (LUAD). This study aims to investigate the cellular mechanism underlyin...
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Article
The relationship between perfectionism and depressive symptoms among Chinese college students: The mediating roles of self-compassion and impostor syndrome
Using a longitudinal research approach, we assessed 1865 college students twice with a six-month interval to reveal the underlying mechanism of perfectionism in depressive symptoms. After controlling for gende...
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Article
Dynamic Output Feedback Control for Asynchronous Switched Systems in Network Environments Subject to Deception Attack
This paper studies the problem of dynamic output feedback control for networked switched systems which suffer from the asynchronism and deception attack. Different from the general asynchronism that only occur...
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Article
Open AccessThin-slice computed tomography enables to classify pulmonary subsolid nodules into pre-invasive lesion/minimally invasive adenocarcinoma and invasive adenocarcinoma: a retrospective study
The aim was to investigate the ability of thin-slice computed tomography (TSCT) to differentiate invasive pulmonary adenocarcinomas (IACs) from pre-invasive/minimally invasive adenocarcinoma (AAH-MIAs), manife...
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Metagenomic Screening of a Novel PET Esterase via In Vitro Expression System
Metagenomic screening is a widely applied biotechnological approach for screening of novel industrial enzymes. The traditional method of metagenomic screening is based on the functional analyses of heterologou...
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Article
Open AccessA novel metagenome-derived viral RNA polymerase and its application in a cell-free expression system for metagenome screening
The mining of genomes from non-cultivated microorganisms using metagenomics is a powerful tool to discover novel proteins and other valuable biomolecules. However, function-based metagenome searches are often ...
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Article
Estimation of Tempered Stable Lévy Models of Infinite Variation
Truncated realized quadratic variations (TRQV) are among the most widely used high-frequency-based nonparametric methods to estimate the volatility of a process in the presence of jumps. Nevertheless, the trun...
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Article
Open AccessClinicopathologic features and genomic analysis of pulmonary blastomatoid carcinosarcoma
This study was designed to investigate the clinicopathologic features of pulmonary blastomatoid carcinosarcoma and explore the genomic profiles of epithelial and mesenchymal components in this tumor.
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Article
Open AccessDiaphragmatic dysfunction associates with dyspnoea, fatigue, and hiccup in haemodialysis patients: a cross-sectional study
Muscle wasting is associated with increased mortality and morbidity in chronic kidney disease (CKD) patients, especially in the haemodialysis (HD) population. Nevertheless, little is known regarding diaphragm ...
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Article
Clinicopathological Features of ALK Expression in 9889 Cases of Non-small-Cell Lung Cancer and Genomic Rearrangements Identified by Capture-Based Next-Generation Sequencing: A Chinese Retrospective Analysis
The clinicopathological features and genomic rearrangements of anaplastic lymphoma kinase (ALK) fusion cases have not been fully identified.
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Article
Open AccessMalignant perivascular epithelioid cell tumor of the lung synchronous with a primary adenocarcinoma: one case report and review of the literature
Perivascular Epithelioid Cell Tumors (PEComa) is an extraordinarily rare mesenchymal neoplasm especially the malignant type originating from the lung. To date, only 8 cases of malignant or malignant potential ...
