1,907 Result(s)
-
Article
Open AccessPrognostic and therapeutic implications of TP53 expression in chronic myelomonocytic leukemia
-
Article
Open AccessDeep Learning–Based Localization and Detection of Malpositioned Nasogastric Tubes on Portable Supine Chest X-Rays in Intensive Care and Emergency Medicine: A Multi-center Retrospective Study
Malposition of a nasogastric tube (NGT) can lead to severe complications. We aimed to develop a computer-aided detection (CAD) system to localize NGTs and detect NGT malposition on portable chest X-rays (CXRs)...
-
Article
Open AccessOptimizing immunofluorescence with high-dynamic-range imaging to enhance PD-L1 expression evaluation for 3D pathology assessment from NSCLC tumor tissue
Assessing programmed death ligand 1 (PD-L1) expression through immunohistochemistry (IHC) is the golden standard in predicting immunotherapy response of non-small cell lung cancer (NSCLC). However, observation...
-
Article
Open AccessPreoperative neutrophil–to–lymphocyte ratio after chemoradiotherapy for esophageal squamous cell carcinoma associates with postoperative pulmonary complications following radical esophagectomy
Esophagectomy after chemoradiotherapy is associated with an increased risk of surgical complications. The significance of preoperative neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio after chem...
-
Article
Dynamic change of metabolic dysfunction-associated steatotic liver disease in patients with hepatitis C virus infection after achieving sustained virologic response with direct-acting antivirals
Information on the dynamics of metabolic dysfunction-associated steatotic liver disease (MASLD) among hepatitis C virus patients achieving sustained virologic response (SVR12) with direct-acting antivirals (DAAs)...
-
Article
Open AccessVascular endothelial dysfunction induced by 3-bromofluoranthene via MAPK-mediated-NFκB pro-inflammatory pathway and intracellular ROS generation
3-Bromofluoranthene (3-BrFlu) is the secondary metabolite of fluoranthene, which is classified as a polycyclic aromatic hydrocarbon, through bromination and exists in the fine particulate matter of air polluta...
-
Article
Validation of the constitution in Chinese medicine questionnaires with the newly developed blood-vacuity category: a rare Taiwanese case study
The concept of body constitution (BC) is a core notion in traditional Chinese medicine, used in diagnosis, treatment, and prevention; however, there is little standardization in terms of definitions and measur...
-
Article
Three-Month Excessive Body Weight Loss < 37.7% as a Predictor of Mid-term Suboptimal Outcomes Postlaparoscopic Sleeve Gastrectomy: Risk Factors and the Impact of Neutrophil-to-Lymphocyte Ratio on Adipocyte Function
This study aimed to evaluate the impact of achieving < 37.7% excess body-weight loss (EBWL) within 3 months of postlaparoscopic sleeve gastrectomy (LSG) on clinical outcomes and its correlation with adipocyte ...
-
Article
Open AccessDevelo** an entrustable professional activity for providing health education and consultation in occupational therapy and examining its validity
Entrustable Professional Activities (EPA)-based assessment is easily and intuitively used in evaluating the learning outcomes of competency-based medical education (CBME). This study aimed to develop an EPA fo...
-
Article
Open AccessUnderstanding and alleviating informal caregiver burden through the development and validation of a caregiver strain index-based model in Taiwan
Quantifying the informal caregiver burden is important for understanding the risk factors associated with caregiver overload and for evaluating the effectiveness of services provided in Long-term Care (LTC).
-
Article
Open AccessTransposase-assisted target-site integration for efficient plant genome engineering
The current technologies to place new DNA into specific locations in plant genomes are low frequency and error-prone, and this inefficiency hampers genome-editing approaches to develop improved crops1,2. Often co...
-
Article
Temporal Trends in Survival Outcomes for Patients with Esophageal Cancer Following Neoadjuvant Chemoradiotherapy: A 14-Year Analysis
The prognosis for patients with esophageal cancer who received neoadjuvant chemoradiotherapy (nCRT) followed by surgery has shown improvement in recent years. We sought to identify the critical factors contrib...
-
Article
Open AccessSex differences in the association of long-term exposure to heat stress on kidney function in a large Taiwanese population study
The incidence and prevalence of dialysis in Taiwan are high compared to other regions. Consequently, mitigating chronic kidney disease (CKD) and the worsening of kidney function have emerged as critical health...
-
Article
Open AccessThe risk of herpes zoster is positively associated with obesity, especially morbid obesity
This study aimed to investigate the association between obesity and herpes zoster (HZ) occurrence. This study used data covering 2 million people in Taiwan in 2000, which were obtained from the National Health...
-
Article
Differentiation in theta and gamma activation in weight-shifting learning between people with parkinson’s disease of different anxiety severities
Anxiety and postural control deficits may be related in people with Parkinson’s disease (PwPD). However, the association between anxiety levels and weight-shifting control remains ambiguous. This study investi...
-
Article
Accounting conservatism, corporate diversification and firm value
This study investigates the impact of conservative financial reporting on corporate diversification, in order to explore whether accounting policy plays a role in mitigating agency problems associated with cor...
-
Article
Open AccessRegulation of primary cilia disassembly through HUWE1-mediated TTBK2 degradation plays a crucial role in cerebellar development and medulloblastoma growth
Development of the cerebellum requires precise regulation of granule neuron progenitor (GNP) proliferation. Although it is known that primary cilia are necessary to support GNP proliferation, the exact molecul...
-
Article
Open AccessSpliceAPP: an interactive web server to predict splicing errors arising from human mutations
Splicing variants are a major class of pathogenic mutations, with their severity equivalent to nonsense mutations. However, redundant and degenerate splicing signals hinder functional assessments of sequence v...
-
Article
Open AccessExamining customer intentions to purchase intelligent robotic products and services in Taiwan using the theory of planned behaviour
The literature for assessing online and offline shop** behaviours that are linked to intelligent robotic goods and services is inadequate. In this study, we applied the Theory of Planned Behaviour model for ...
-
Article
Open AccessEffectiveness of fentanyl buccal soluble film in cancer patients with inadequate breakthrough pain control
Clinical evidence for the rapidity and effectiveness of fentanyl buccal soluble film (FBSF) in reducing pain intensity of breakthrough cancer pain (BTcP) remains inadequate. This study aimed to evaluate the ef...