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  1. No Access

    Article

    Mott neurons with dual thermal dynamics for spatiotemporal computing

    Heat dissipation is a natural consequence of operating any electronic system. In nearly all computing systems, such heat is usually minimized by design and cooling. Here, we show that the temporal dynamics of ...

    Gwangmin Kim, Jae Hyun In, Younghyun Lee, Hakseung Rhee, Woojoon Park in Nature Materials (2024)

  2. Article

    Open Access

    Probabilistic computing with NbOx metal-insulator transition-based self-oscillatory pbit

    Energy-based computing is a promising approach for addressing the rising demand for solving NP-hard problems across diverse domains, including logistics, artificial intelligence, cryptography, and optimization...

    Hakseung Rhee, Gwangmin Kim, Hanchan Song, Woojoon Park in Nature Communications (2023)

  3. Article

    Open Access

    Improving radiation dosimetry with an automated micronucleus scoring system: correction of automated scoring errors

    Radiation dose estimations performed by automated counting of micronuclei (MN) have been studied for their utility for triage following large-scale radiological incidents; although speed is essential, it also ...

    Younghyun Lee, Young Woo **, Ki Moon Seong in Radiation and Environmental Biophysics (2023)

  4. Article

    Open Access

    Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques

    Non-human primates, such as Rhesus macaques, are a powerful model for studies of the cellular and physiological effects of radiation, development of radiation biodosimetry, and for understanding the impact of ...

    Shanaz A. Ghandhi, Shad R. Morton, Igor Shuryak, Younghyun Lee in BMC Genomics (2023)

  5. No Access

    Protocol

    High-Throughput γ-H2AX Assay Using Imaging Flow Cytometry

    The γ-H2AX assay is a sensitive and reliable method to evaluate radiation-induced DNA double-strand breaks. The conventional γ-H2AX assay detects individual nuclear foci manually, but is labor-intensive and ti...

    Younghyun Lee, Qi Wang, Ki Moon Seong, Helen C. Turner in Spectral and Imaging Cytometry (2023)

  6. No Access

    Article

    Interventional radiologists have a higher rate of chromosomal damage due to occupational radiation exposure: a dicentric chromosome assay

    There are growing concerns regarding radiation exposure in medical workers who perform interventional fluoroscopy procedures. Owing to the nature of certain interventional procedures, workers may be subjected ...

    Younghyun Lee, Won ** Lee, Young Woo **, Seongjae Jang in European Radiology (2021)

  7. No Access

    Article

    Catalytic production of hexamethylenediamine from renewable feedstocks

    Renewable biomass-derived chemicals have received considerable interest as a potential substitute for petroleum-derived chemicals. Hexamethylenediamine is a key intermediate in manufacturing nylon 66, a synthe...

    Jechan Lee, Younghyun Lee, Soosan Kim in Korean Journal of Chemical Engineering (2021)

  8. No Access

    Chapter and Conference Paper

    Rotated Box Is Back: An Accurate Box Proposal Network for Scene Text Detection

    Scene text detection is a challenging task because it must be able to handle text in various fonts and from various perspective views. This makes it difficult to use rectangular bounding boxes to detect text l...

    Jusung Lee, Jaemyung Lee, Cheoljong Yang in Document Analysis and Recognition – ICDAR … (2021)

  9. Article

    Open Access

    Development of the FAST-DOSE assay system for high-throughput biodosimetry and radiation triage

    Following a large-scale radiological incident, there is a need for FDA-approved biodosimetry devices and biomarkers with the ability to rapidly determine past radiation exposure with sufficient accuracy for ea...

    Qi Wang, Younghyun Lee, Igor Shuryak, Monica Pujol Canadell in Scientific Reports (2020)

  10. No Access

    Article

    Recent Progress in Inorganic Hole Transport Materials for Efficient and Stable Perovskite Solar Cells

    Organic–inorganic hybrid perovskite solar cells (PSCs) are considered as one of the most promising emerging photovoltaics with outstanding performance. However, the commonly used organic hole transport materia...

    Bum** Gil, Alan Jiwan Yun, Younghyun Lee, **hyun Kim in Electronic Materials Letters (2019)

  11. Article

    Open Access

    Development of a high-throughput γ-H2AX assay based on imaging flow cytometry

    Measurement of γ-H2AX foci levels in cells provides a sensitive and reliable method for quantitation of the radiation-induced DNA damage response. The objective of the present study was to develop a rapid, hig...

    Younghyun Lee, Qi Wang, Igor Shuryak, David J. Brenner in Radiation Oncology (2019)

  12. No Access

    Article

    Polymers derived from hemicellulosic parts of lignocellulosic biomass

    Furfural, which is directly derived from the hemicellulosic parts of lignocellulosic biomass, is considered as one of the most promising platform chemicals to manufacture commodity chemical products such as po...

    Younghyun Lee, Eilhann E. Kwon, Jechan Lee in Reviews in Environmental Science and Bio/T… (2019)

  13. Article

    Open Access

    Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and spleen mononuclear cells in vivo following Cesium-137 administration

    Cesium-137 (137Cs) is one of the major and most clinically relevant radionuclides of concern in a radiological dispersal device, “dirty bomb” scenario as well as in nuclear accidents and detonations. In this expo...

    Helen C. Turner, Younghyun Lee, Waylon Weber in BMC Molecular and Cell Biology (2019)

  14. Article

    Open Access

    Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model

    After a radiological incident, there is an urgent need for fast and reliable bioassays to identify radiation-exposed individuals within the first week post exposure. This study aimed to identify candidate radi...

    Younghyun Lee, Monica Pujol Canadell, Igor Shuryak, Jay R. Perrier in Scientific Reports (2018)

  15. No Access

    Article

    Design parametric study on the influence of anti-shock performance during operational condition for a 2.5 inch HDD

    This study investigated the effect of design parameters of a 2.5 inch HDD on the operational shock (op-shock) performance, including the base, cover, ramp stiffness, and the e-block, disk thickness. First, tra...

    Geonyup Lim, Kyoung-Su Park, No-Cheol Park, Young-Pil Park in Microsystem Technologies (2015)

  16. Article

    Open Access

    VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation

    High linear energy transfer (LET) radiation such as carbon ion particles is successfully used for treatment of solid tumors. The reason why high LET radiation accomplishes greater tumor-killing than X-rays is ...

    Hiroshi Fujisawa, Nakako Izumi Nakajima, Shigeaki Sunada in Radiation Oncology (2015)

  17. Article

    Open Access

    Selective Effects of Curcumin on CdSe/ZnS Quantum-dot-induced Phototoxicity Using UVA Irradiation in Normal Human Lymphocytes and Leukemia Cells

    Quantum dots (QDs) have received considerable attention due to their potential role in photosensitization during photodynamic therapy. Although QDS are attractive nanomaterials due to their novel and unique ph...

    Soomin Goo, Young Joo Choi, Younghyun Lee, Sunyeong Lee in Toxicological Research (2013)

  18. No Access

    Article

    Dynamic time war** based identification using gabor feature of Adaptive Motion Model for walking humans

    In this paper, we propose a novel feature extraction method for the identification of humans. The main objective of our method is to identify each human being by extracting the Gabor feature based on the Adapt...

    Junbum Park, Younghyun Lee, Hanseok Ko in International Journal of Control, Automati… (2009)

  19. No Access

    Article

    Dexamethasone 21-Sulfate Improves the Therapeutic Properties of Dexamethasone Against Experimental Rat Colitis by Specifically Delivering the Steroid to the Large Intestine

    We investigated in vivo-colon targetability and therapeutic properties of DS against experimental rat colitis.

    Inho Kim, Hyesik Kong, Younghyun Lee, Sungchae Hong, Jungoh Han in Pharmaceutical Research (2009)