16 Result(s)

Article

Exosomal circRNA-100338 promotes hepatocellular carcinoma metastasis via enhancing invasiveness and angiogenesis

Exosomes play crucial roles in regulating the crosstalk between normal and cancer cells in the tumor microenvironment, and in regulating cancer proliferation, migration and invasion through their cargo molecules.

**u-Yan Huang, Zi-Li Huang, ** Huang… in Journal of Experimental & Clinical Cancer … (2020)

Article

Systematic analysis of gene expression profiles reveals prognostic stratification and underlying mechanisms for muscle-invasive bladder cancer

Muscle-invasive bladder cancer (MIBC) is originated in the muscle wall of the bladder, and is the ninth most common malignancy worldwide. However, there are no reliable, accurate and robust gene signatures for...

**-Bao Zhang, Zi-Li Huang, Yong-Hua Xu, ** Huang… in Cancer Cell International (2019)

Article

Comprehensive circular RNA profiling reveals the regulatory role of the circRNA-100338/miR-141-3p pathway in hepatitis B-related hepatocellular carcinoma

Circular RNAs (circRNAs) represent a class of endogenous noncoding RNAs that have recently been recognized as important regulators of gene expression and pathological networks. However, their transcriptional a...

**u-Yan Huang, Zi-Li Huang, Yong-Hua Xu, Qi Zheng, Zi Chen, Wei Song… in Scientific Reports (2017)

Article

Erratum to: Pancreatic cancer cell-derived IGFBP-3 contributes to muscle wasting

**u-yan Huang, Zi-li Huang, Ju-hong Yang… in Journal of Experimental & Clinical Cancer … (2016)

Article

Pancreatic cancer cell-derived IGFBP-3 contributes to muscle wasting

Progressive loss of skeletal muscle, termed muscle wasting, is a hallmark of cancer cachexia and contributes to weakness, reduced quality of life, as well as poor response to therapy. Previous studies have ind...

**u-yan Huang, Zi-li Huang, Ju-hong Yang… in Journal of Experimental & Clinical Cancer … (2016)

Article

Herbal compound "Songyou Yin" reinforced the ability of interferon-alfa to inhibit the enhanced metastatic potential induced by palliative resection of hepatocellular carcinoma in nude mice

Liver resection is a widely accepted treatment for hepatocellular carcinoma (HCC). Our previous clinical study showed that the rate of palliative resection was 34.0% (1958-2008, 2754 of 8107). However, the inf...

**u-Yan Huang, Zi-Li Huang, Lu Wang, Yong-Hua Xu, **n-Yu Huang, Kai-**ng Ai… in BMC Cancer (2010)

Article

The associated regulators and signal pathway in rIL-16/CD4 mediated growth regulation in Jurkat cells

IL-16 is a ligand and chemotactic factor for CD4⁺ T cells. IL-16 inhibits the CD3 mediated lymphocyte activation and proliferation. The effects of IL-16 on the target cells are dependent on the cell type, the pre...

**ao Ming ZHANG, Yong Hua XU in Cell Research (2002)

Article

Cloning and characterization of a mouse liver-specific gene mfrep-1, upregulated in liver regeneration

Human fibrinogen-related protein-1/liver fibrinogen-related protein-1 (HFREP-1/LFIRE-1), a liver-specific protein, is a member of fibrinogen superfamily that exerts various biological activities. However, the ...

Jun YAN, Hao YING, Fei GU, ** HE, Yu Li LI, Hui Min LIU, Yong Hua XU in Cell Research (2002)

Article

Down-regulated expression of atypical PKC-binding domain deleted asip isoforms in human hepatocellular carcinomas

Asip is a mammalian homologue of polarity protein Par-3 of Caenorhabditis elegans and Bazooka of Drosophila melanogaster. Asip/Par-3/Bazooka are PDZ-motif containing proteins that localize asymmetrically to th...

Chang Ming FANG, Yong Hua XU in Cell Research (2001)

Article

Bcl-2 over-expression and activation of protein kinase C suppress the Trail-induced apoptosis in Jurkat T cells

Trail, a tumor necrosis factor-related apoptosis-inducing ligand, is a novel potent endogenous activator of the cell death pathway through the activation of cell surface death receptors Trail-R1 and Trail-R2. ...

Ben Chang GUO, Yong Hua XU in Cell Research (2001)

Article

Expression of Bcl-2 inhibited Fas-mediated apoptosis in human hepatocellular carcinoma BEL-7404 cells

Apoptosis plays an important role in embryonic development, tissue remodeling, immune regulation and tumor regression. Two groups of molecules (Bcl-2 family and “Death factor” family) are involved in regulatin...

Yun Chao CHANG, Yong Hua XU in Cell Research (2000)

Article

Deregulated c-myc expression in quiescent CHO cells induces target gene transcription and subsequent apoptotic phenotype

Human c-myc cDNA was fused with the hormone-binding domain (HBD) cDNA of murine estrogen receptor gene and the chimeric gene was introduced into the CHO cells. The fusion protein, c-MycER, becomes activated wh...

Chang Ming FANG, Can SHI, Yong Hua XU in Cell Research (1999)

Article

mad-overexpression down regulates the malignant growth and p53 mediated apoptosis in human hepatocellular carcinoma BEL-7404 cells

Mad protein has been shown as an antagonist of c-Mycprotein in some cell lines. The effect of Mad protein to the malignant phenotype of human hepatoma BEL-7404 cell line was investigated experimentally. An euk...

Hua ZHAO, Yong Hua XU in Cell Research (1999)

Article

Antisense EGFR sequence enhances apoptosis in a human hepatoma cell line BEL-7404

Effects of antisense epidermal growth factor receptor(EGFR) sequence on apoptotic cell death were examined in a human hepatoma cell line BEL-7404 cells. In the cells of JX-1, a sub clone of BEL-7404 stably tra...

Tao Fu, He Liu, Fan Liu, Jun Gu, Wan Li Jiang, Yong Hua Xu in Cell Research (1996)