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Article
Electrochemical Detection of Pb(II) Ions in Aqueous Solution by Carbon Nanospheres Modified Boron-Doped Diamond Electrode
In this paper, a sensor using carbon nanospheres modified boron-doped diamond (CNs/BDD) electrode for detecting heavy metal ions rapidly in aqueous solution is studied. The CNs/BDD electrode is characterized s...
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Article
Open AccessShort cell-penetration peptide conjugated bioreducible polymer enhances gene editing of CRISPR system
CRISPR-based gene therapy offers precise targeting and specific editing of disease-related gene sequences, potentially yielding long-lasting treatment effects. However, efficient delivery remains a significant...
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Article
3D printed anti-swelling hydrogel scaffold with dialdehyde cellulose nanocrystals
In this study, a novel hydrogel preparation method was developed to formulate a 3D printable hydrogel with low swelling ratio for biomedical scaffolds. Nanocellulose fibrils were first oxidized to synthesize d...
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Article
Molecularly imprinted dispersive micro solid-phase extraction and tandem derivatization for the determination of histamine in fermented wines
Histamine causes allergic reactions and can serve as an indicator for assessing food quality. This study designed and developed a dispersive micro solid-phase extraction (D-μSPE) method that combined the advan...
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Article
Fabrication of Dual-Functional Micelles Based on Star-Shaped Copolymer for Bioimaging
Dual-modal fluorescent/magnetic resonance imaging attracts more and more attentions in biomedical applications. Herein, star-shaped poly(ε-caprolactone)-b-poly(N-vinylpyrrolidone) amphiphilic copolymer with a tet...
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Article
An efficient electrocatalytic catalyst for hydrogen production: MoS2/Cu2S/PANI with 'wheat ear' structure
In this study, MoS2/Cu2S/PANI with ‘wheat ear' structure was synthesized on nickel foam (NF) for electrocatalytic hydrogen production. The experimental results show that the catalyst exhibits excellent HER perfor...
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Article
Neuroprotective Effects of Lycium Barbarum Fruit Extract on Pink1B9Drosophila Melanogaster Genetic Model of Parkinson’s Disease
Lycium barbarum (LB) is a famous traditional Chinese medicinal plant as well as food supplement possessing various pharmacological functions such as anti-aging and antioxidant effects. The Parkinson’s disease (PD...
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Reference Work Entry In depth
Nanodendrite a Promising Material for Bioanalytical Application
Multidisciplinary initiatives in the area of nanomedicine for biological applications have made significant progress toward overcoming typical constraints of conventional drug delivery, which including poor bi...
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Article
Open AccessMultiplexed evaluation of immunity against SARS-CoV-2 variants using surface enhanced fluorescence from a nanostructured plasmonic chip
Generated by the immune system post-infection or through vaccination, the effectiveness of antibodies against emerging SARS-CoV-2 variants is crucial for protecting individuals from the COVID-19 pandemic. Here...
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Article
Highly compressible hydrogel reinforced with cellulose nanocrystals for ultrasound scanning via microwave-assisted synthesis
In this study, a rapid fabrication method was developed to prepare hydrogel structures with high mechanical strength and low attenuation coefficient for ultrasound scanning. Poly acrylic acid (PAA) hydrogel wa...
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Article
First-Principles Study of Two-Dimensional Layered MoSi2N4 and WSi2N4 for Photocatalytic Water Splitting
Two-dimensional (2D) materials have attracted increasing interest due to their excellent properties and various applications such as energy storage, sensors, composites and catalysis. Recently, 2D van der Waal...
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Article
Functional Teas from Penthorum chinense Pursh Alleviates Ethanol-Induced Hepatic Oxidative Stress and Autophagy Impairment in Zebrafish via Modulating the AMPK/p62/Nrf2/mTOR Signaling Axis
Penthorum chinense Pursh (PCP), a medicinal and edible plant, is widely used in many clinical liver diseases. Oxidative stress and autophagy impairment play crucial roles in the pathophysiology of alcoholic liver...
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Article
Open AccessHighly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of Alzheimer's disease via NLRP3-inhibition
Alzheimer's disease (AD) is the most common neurodegenerative disorder without effective therapy and lack diagnosis strategy for preclinical AD patients. There is an urgent need for development of both early d...
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Article
Density functional methods study on the structures and spectral characteristics for pharmacophoric conformers, metabolites, and combined fragments of Erlotinib
Erlotinib is an essential drug for the clinical treatment of non-small cell lung cancer, pancreatic cancer, and other cancers. Erlotinib tends to be conformation A rather than the pharmacophoric conformation B in...
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Article
Bacterial cellulose reinforced with skim/fresh natural rubber latex for improved mechanical, chemical and dielectric properties
Bacterial cellulose (BC) was reinforced via immersion in diluted skim natural rubber (SNR) latex and fresh natural rubber (FNR) latex to improve the mechanical, chemical and dielectric properties. The effects ...
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Article
Open AccessDye-loaded mesoporous polydopamine nanoparticles for multimodal tumor theranostics with enhanced immunogenic cell death
Tumor phototherapy especially photodynamic therapy (PDT) or photothermal therapy (PTT), has been considered as an attractive strategy to elicit significant immunogenic cell death (ICD) at an optimal tumor rete...
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Article
Open AccessAmorphous calcium phosphate nanoparticles using adenosine triphosphate as an organic phosphorus source for promoting tendon–bone healing
Rotator cuff tear (RCT) is a common problem of the musculoskeletal system. With the advantage of promoting bone formation, calcium phosphate materials have been widely used to augment tendon-bone healing. Howe...
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Article
Open AccessBroadening the biocompatibility of gold nanorods from rat to Macaca fascicularis: advancing clinical potential
The biomedical field has used gold nanorods (GNRs) for decades; however, clinical trials and translation is limited except gold nanoshells. The preparation of gold nanoshells is more complex than that of polye...
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Article
Open AccessSuccessful biosynthesis of natural antioxidant ergothioneine in Saccharomyces cerevisiae required only two genes from Grifola frondosa
Ergothioneine (EGT) has a unique antioxidant ability and diverse beneficial effects on human health. But the content of EGT is very low in its natural producing organisms such as Mycobacterium smegmatis and mushr...
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Article
Rapid and Sensitive Detection of Isoproturon Via an Electrochemical Sensor Based on Highly Water-Dispersed Carbon Hybrid Material
Isoproturon (ISO), an herbicide belonging to the phenyl urea family, is extensively used in modern agriculture to guarantee a bumper harvest. However, it has been evidenced that the ISO has heavy toxicity to t...