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Article
Molecularly imprinted dispersive micro solid-phase extraction and tandem derivatization for the determination of histamine in fermented wines
Histamine causes allergic reactions and can serve as an indicator for assessing food quality. This study designed and developed a dispersive micro solid-phase extraction (D-μSPE) method that combined the advan...
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Article
In silico prediction of parkinsonian motor deficits-related neurotoxicants based on the adverse outcome pathway concept
Exposure to neurotoxicants has been associated with Parkinson's disease (PD). Limited by the clinical variation in the signs and symptoms as well as the slow disease progression, the identification of parkinso...
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Article
Open AccessCorrection: Enhancing Cross-lingual Biomedical Concept Normalization Using Deep Neural Network Pretrained Language Models
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Article
Open AccessEnhancing Cross-lingual Biomedical Concept Normalization Using Deep Neural Network Pretrained Language Models
In this study, we propose a new approach for cross-lingual biomedical concept normalization, the process of map** text in non-English documents to English concepts of a knowledge base. The resulting map**s...
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Chapter and Conference Paper
A Learning-Based Approach to Combine Medical Annotation Results
There exist many tools to annotate mentions of medical entities in documents with concepts from biomedical ontologies. To improve the overall quality of the annotation process, we propose the use of machine le...
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Chapter and Conference Paper
Combining Semantic and Lexical Measures to Evaluate Medical Terms Similarity
The use of similarity measures in various domains is cornerstone for different tasks ranging from ontology alignment to information retrieval. To this end, existing metrics can be classified into several categ...
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Article
Evolving semantic annotations through multiple versions of controlled medical terminologies
The extensive use of semantic annotations in the medical domain to enhance information retrieval or encode clinical notes to improving information reuse and sharing demands for high quality annotations generat...
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Article
Open AccessIdentification of informative features for predicting proinflammatory potentials of engine exhausts
The immunotoxicity of engine exhausts is of high concern to human health due to the increasing prevalence of immune-related diseases. However, the evaluation of immunotoxicity of engine exhausts is currently b...
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Article
Open AccessSkinSensDB: a curated database for skin sensitization assays
Skin sensitization is an important toxicological endpoint for chemical hazard determination and safety assessment. Prediction of chemical skin sensitizer had traditionally relied on data from rodent models. Th...
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Article
Open AccessA derivatization-enhanced detection strategy in mass spectrometry: analysis of 4-hydroxybenzoates and their metabolites after keratinocytes are exposed to UV radiation
4-Hydroxybenzoate is a phenolic derivative of alkyl benzoates and is a widely used preservative in cosmetic and pharmaceutical products. The presence of 4-hydroxybenzoates in the human body may result from the...
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Chapter and Conference Paper
Evaluating and Improving Annotation Tools for Medical Forms
The annotation of entities with concepts from standardized terminologies and ontologies is of high importance in the life sciences to enhance semantic interoperability, information retrieval and meta-analysis....
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Chapter and Conference Paper
Prediction of Proinflammatory Potentials of Engine Exhausts by Integrating Chemical and Biological Features
The increasing prevalence of immune-related diseases has raised concerns about immunotoxicity of engine exhausts. The evaluation of immunotoxicity associated with engine exhausts has relied on expensive and ti...
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Chapter and Conference Paper
Leveraging the Impact of Ontology Evolution on Semantic Annotations
This paper deals with the problem of maintenance of semantic annotations produced based on domain ontologies. Many annotated texts have been produced and made available to end-users. If not reviewed regularly,...
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Article
Open AccessAssembly of eukaryotic algal chromosomes in yeast
Synthetic genomic approaches offer unique opportunities to use powerful yeast and Escherichia coli genetic systems to assemble and modify chromosome-sized molecules before returning the modified DNA to the target...
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Article
Conservation of Heathland Ground Beetles (Coleoptera, Carabidae): The Value of Lowland Coniferous Plantations
The value of conifer-dominated plantation forestry for heathland carabids is examined, in Breckland, eastern England. Historically dominated by heathland habitats supporting scarce species of restricted distri...
