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Article
Open AccessRevisiting the complexity of and algorithms for the graph traversal edit distance and its variants
The graph traversal edit distance (GTED), introduced by Ebrahimpour Boroojeny et al. (2018), is an elegant distance measure defined as the minimum edit distance between strings reconstructed from Eulerian trai...
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Chapter and Conference Paper
Graph-Based Genome Inference from Hi-C Data
Three-dimensional chromosome structure plays an important role in fundamental genomic functions. Hi-C, a high-throughput, sequencing-based technique, has drastically expanded our comprehension of 3D chromosome...
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Article
Open AccessThe role of NPY2R/NFATc1/DYRK1A regulatory axis in sebaceous glands for sebum synthesis
Sebaceous glands (SGs) synthesize and secret sebum to protect and moisturize the dermal system via the complicated endocrine modulation. Dysfunction of SG are usually implicated in a number of dermal and infla...
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Article
Open AccessDe novo design of modular peptide-binding proteins by superhelical matching
General approaches for designing sequence-specific peptide-binding proteins would have wide utility in proteomics and synthetic biology. However, designing peptide-binding proteins is challenging, as most pept...
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Article
Genomic distribution of signal transducer and activator of transcription (STAT) family in colorectal cancer
JAK/STAT pathway has been widely acknowledged in the development of human cancers. However, the role of different phosphorylated STAT proteins translocating into nucleus in transcription activation of target g...
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Article
Open AccessTranscriptome-scale spatial gene expression in rat arcuate nucleus during puberty
A variety of neurons in hypothalamus undergo a complicated regulation on transcription activity of multiple genes for hypothalamic–pituitary–gonadal axis activation during pubertal development. Identification ...
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Article
Open AccessInvolvement of FANCD2 in Energy Metabolism via ATP5α
Growing evidence supports a general hypothesis that aging and cancer are diseases related to energy metabolism. However, the involvement of Fanconi Anemia (FA) signaling, a unique genetic model system for stud...
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Article
Claudin 6: a novel surface marker for characterizing mouse pluripotent stem cells