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  1. Article

    Open Access

    Revisiting the complexity of and algorithms for the graph traversal edit distance and its variants

    The graph traversal edit distance (GTED), introduced by Ebrahimpour Boroojeny et al. (2018), is an elegant distance measure defined as the minimum edit distance between strings reconstructed from Eulerian trai...

    Yutong Qiu, Yihang Shen, Carl Kingsford in Algorithms for Molecular Biology (2024)

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  2. No Access

    Chapter and Conference Paper

    Graph-Based Genome Inference from Hi-C Data

    Three-dimensional chromosome structure plays an important role in fundamental genomic functions. Hi-C, a high-throughput, sequencing-based technique, has drastically expanded our comprehension of 3D chromosome...

    Yihang Shen, Lingge Yu, Yutong Qiu… in Research in Computational Molecular Biology (2024)

  3. Article

    Open Access

    The role of NPY2R/NFATc1/DYRK1A regulatory axis in sebaceous glands for sebum synthesis

    Sebaceous glands (SGs) synthesize and secret sebum to protect and moisturize the dermal system via the complicated endocrine modulation. Dysfunction of SG are usually implicated in a number of dermal and infla...

    Tao Yang, Renyi Hei, **aosong Li, Tianhua Ma… in Cellular & Molecular Biology Letters (2023)

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  4. Article

    Open Access

    De novo design of modular peptide-binding proteins by superhelical matching

    General approaches for designing sequence-specific peptide-binding proteins would have wide utility in proteomics and synthetic biology. However, designing peptide-binding proteins is challenging, as most pept...

    Kejia Wu, Hua Bai, Ya-Ting Chang, Rachel Redler, Kerrie E. McNally… in Nature (2023)

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  5. No Access

    Article

    Genomic distribution of signal transducer and activator of transcription (STAT) family in colorectal cancer

    JAK/STAT pathway has been widely acknowledged in the development of human cancers. However, the role of different phosphorylated STAT proteins translocating into nucleus in transcription activation of target g...

    Yan** Hu, Yifen Shen, Yang Zhao, Ying Tang, Chao Liu, Yongchun Gu, Tao Yang… in Human Cell (2023)

  6. Article

    Open Access

    Transcriptome-scale spatial gene expression in rat arcuate nucleus during puberty

    A variety of neurons in hypothalamus undergo a complicated regulation on transcription activity of multiple genes for hypothalamic–pituitary–gonadal axis activation during pubertal development. Identification ...

    Shasha Zhou, Shaolian Zang, Yan** Hu, Yifen Shen, Hua Li… in Cell & Bioscience (2022)

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  7. Article

    Open Access

    Involvement of FANCD2 in Energy Metabolism via ATP5α

    Growing evidence supports a general hypothesis that aging and cancer are diseases related to energy metabolism. However, the involvement of Fanconi Anemia (FA) signaling, a unique genetic model system for stud...

    Panneerselvam Jayabal, Chi Ma, Manoj Nepal, Yihang Shen, Raymond Che… in Scientific Reports (2017)

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  8. Article

    Claudin 6: a novel surface marker for characterizing mouse pluripotent stem cells

    Linlin Wang, Yan Xue, Yihang Shen, Wei Li, Yan Cheng, **aoshuang Yan… in Cell Research (2012)

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