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  1. Article

    Open Access

    Nickel-catalyzed direct stereoselective α-allylation of ketones with non-conjugated dienes

    The development of efficient and sustainable methods for the construction of carbon-carbon bonds with the simultaneous stereoselective generation of vicinal stereogenic centers is a longstanding goal in organi...

    Yi-Xuan Cao, Matthew D. Wodrich, Nicolai Cramer in Nature Communications (2023)

  2. Article

    Open Access

    Cobalt-catalyzed difluoroalkylation of tertiary aryl ketones for facile synthesis of quaternary alkyl difluorides

    The selective incorporation of gem-difluoroalkyl groups into biologically active molecules has long been used as an efficient strategy for drug design and discovery. However, the catalytic C(sp3)-CF2 bond-forming...

    Chao Li, Yi-Xuan Cao, Rui Wang, Yi-Ning Wang, Quan Lan in Nature Communications (2018)