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  1. No Access

    Article

    NOx removal and copper recovery from the leaching process for waste printed circuit boards: performance evaluation and potential environmental impact assessment

    Resource recovery is crucial for small- and medium-sized enterprises to attain a circular economy. The economic benefits of recovering precious metals from electronic waste, such as waste printed circuit board...

    Tse-Lun Chen, Yen-Syun Chen, Pen-Chi Chiang in Environmental Science and Pollution Resear… (2024)

  2. No Access

    Article

    Regioselective electrochemical radical cascade cyclization of internal alkynes to selenated and trifluoromethylated dihydropyran

    Dihydropyran (DHP) compounds are not only found in natural products and bioactive molecules, but also serve as important precursors in organic synthesis. Nonetheless, traditional methods for the construction o...

    Mingming Yu, Tiantian Huang, Lin Zhang, Muhammad Shabbir in Science China Chemistry (2023)

  3. No Access

    Article

    The Robotic Arm Velocity Planning Based on Reinforcement Learning

    In order to improve the performance of the robotic arm effectively, this study established a robotic arm velocity planning model developed by artificial intelligence in the simulation system. The model not onl...

    Hao-Hsuan Huang, Chih-Kai Cheng in International Journal of Precision Enginee… (2023)

  4. Article

    Open Access

    Performance of urinary C–C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis

    Urinary C–C motif chemokine ligand 14 (CCL14) has been described as an effective marker for delayed recovery of acute kidney injury (AKI), yet its efficacy has been found to vary between different trials. The ...

    Yih‑Ting Chen, Heng-Chih Pan, Cheng-Kai Hsu, Chiao-Yin Sun, Chun-Yu Chen in Critical Care (2023)

  5. Article

    Open Access

    Valve turning towards on-cycle in cobalt-catalyzed Negishi-type cross-coupling

    Ligands and additives are often utilized to stabilize low-valent catalytic metal species experimentally, while their role in suppressing metal deposition has been less studied. Herein, an on-cycle mechanism is...

    Xu Luo, Dali Yang, **aoqian He, Shengchun Wang, Dongchao Zhang in Nature Communications (2023)

  6. Article

    Open Access

    Cerebral Semaphorin3D is a novel risk factor for age-associated cognitive impairment

    We previously reported that miR-195 exerts neuroprotection by inhibiting Sema3A and cerebral miR-195 levels decreased with age, both of which urged us to explore the role of miR-195 and miR-195-regulated Sema3...

    Chien-Yuan Chen, Yung-Mei Chao, Ching-Chang Cho in Cell Communication and Signaling (2023)

  7. Article

    Open Access

    Author Correction: Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy

    **g Gao, Bo Hou, Qiwen Zhu, Lei Yang, **ngyu Jiang, Zhifeng Zou in Nature Communications (2022)

  8. Article

    Open Access

    Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol

    No reports exist as to neuroprotective effects associated with topical activation of transient receptor potential melastatin 8 (TRPM8), a noted cold receptor. In the present study, we identified whether activa...

    Shiang-Suo Huang, Hsing-Hui Su, Szu-Yu Chien, Hsin-Yi Chung in Journal of Neuroinflammation (2022)

  9. Article

    Open Access

    Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy

    PROteolysis TArgeting Chimeras (PROTACs) has been exploited to degrade putative protein targets. However, the antitumor performance of PROTACs is impaired by their insufficient tumour distribution. Herein, we ...

    **g Gao, Bo Hou, Qiwen Zhu, Lei Yang, **ngyu Jiang, Zhifeng Zou in Nature Communications (2022)

  10. Article

    Open Access

    Associations of thiazide use with skin cancers: a systematic review and meta-analysis

    Previous findings on the associations of thiazide use with skin cancers were conflicting. This study aimed to examine the associations of individual thiazide use with skin cancer risk, differentiated by subtyp...

    Shih-Chieh Shao, Chien-Cheng Lai, Yi-Hung Chen, Edward Chia-Cheng Lai in BMC Medicine (2022)

  11. No Access

    Article

    Association between exposure to road traffic noise and hearing impairment: a case-control study

    Noise pollution in urban areas is increasing steadily, and the study of road traffic noises and their effects on the auditory system was rare. This study investigated the potential effects of road traffic nois...

    Tang-Chuan Wang, Ta-Yuan Chang in Journal of Environmental Health Science an… (2021)

  12. Article

    Open Access

    Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus

    Post-traumatic stress disorder (PTSD) is a trauma-related disorder that is associated with pro-inflammatory activation and neurobiological impairments in the brain and leads to a series of affective-like behav...

    Yi-Hung Chen, Sheng-Yun **e, Chao-Wei Chen, Dah-Yuu Lu in Molecular Brain (2021)

  13. Article

    Open Access

    Electroacupuncture prevents cocaine-induced conditioned place preference reinstatement and attenuates ΔFosB and GluR2 expression

    Acupuncture has been used for treating drug addiction since the 1970s, but little is known about the mechanisms by which acupuncture affects drug cue-induced relapse. The transcription factor delta-FosB (ΔFosB...

    Ai T. M. Nguyen, Tran V. B. Quach, Peddanna Kotha, Szu-Yu Chien in Scientific Reports (2021)

  14. No Access

    Article

    Electrochemical oxidative aminocarbonylation of terminal alkynes

    Palladium-catalysed oxidative carbonylation using oxygen as the oxidant is an economical approach; however, the gas mixture of CO and air has an explosive limit of 12.5–74.0% that could hamper extensive applic...

    Li Zeng, Haoran Li, **gcheng Hu, Dongchao Zhang, Jiayu Hu, Pan Peng in Nature Catalysis (2020)

  15. No Access

    Article

    CO2 mineralization and utilization by alkaline solid wastes for potential carbon reduction

    CO2 mineralization and utilization using alkaline solid wastes has been rapidly developed over the last ten years and is considered one of the promising technologies to stabilize solid wastes while combating glob...

    Shu-Yuan Pan, Yi-Hung Chen, Liang-Shih Fan, Hyunook Kim, **ang Gao in Nature Sustainability (2020)

  16. Article

    Galantamine Inhibits Aβ1–42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ1–42 Engulfment During Autophagic Degradation

    Despite Alzheimer’s disease (AD) being the most common neurodegenerative disorder worldwide, no FDA-approved disease-modifying treatments have been approved for this condition since 2003. Neuronal-type alpha7 ...

    Ming-Wei Lin, Yi-Hung Chen, Han-Ben Yang, Chi Chien Lin, Shih-Ya Hung in Neurotherapeutics (2020)

  17. Article

    Open Access

    Inhibiting the LPS-induced enhancement of mEPSC frequency in superficial dorsal horn neurons may serve as an electrophysiological model for alleviating pain

    Pain is a major primary health care problem. Emerging studies show that inhibition of spinal microglial activation reduces pain. However, the precise mechanisms by which microglial activation contributes to no...

    Chin-Tsang Yang, Shih-Ya Hung, Sheng-Feng Hsu, Iona MacDonald in Scientific Reports (2019)

  18. Article

    Open Access

    Direct electrochemical oxidation of alcohols with hydrogen evolution in continuous-flow reactor

    Alcohol oxidation reactions are widely used for the preparation of aldehydes and ketones. The electrolysis of alcohols to carbonyl compounds have been underutilized owing to low efficiency. Herein, we report a...

    Dan Wang, Pan Wang, Shengchun Wang, Yi-Hung Chen, Heng Zhang in Nature Communications (2019)

  19. No Access

    Article

    Kinetic modeling of 1-decene oligomerization to synthetic fuels and base oil over tungstated-zirconia catalyst

    The liquid phase oligomerization reaction of 1-decene to produce dimers and trimers was performed in a semi-batch autoclave reactor over a tungstated-zirconia catalyst at different reaction temperatures. While...

    Tattep Techopittayakul, Snunkheam Echaroj in Reaction Kinetics, Mechanisms and Catalysis (2019)

  20. Article

    Phoenixin: a novel brain-gut-skin peptide with multiple bioactivity

    In this brief review we summarize the current fndings relative to the discovery of a small peptide ligand, phoenixin (PNX). Using a bioinformatic approach, two novel peptides PNX-14 and PNX-20 containing 14 an...

    Rong-Ming Lyu, Alan Cowan, Ying Zhang, Yi-Hung Chen in Acta Pharmacologica Sinica (2018)

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