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NOx removal and copper recovery from the leaching process for waste printed circuit boards: performance evaluation and potential environmental impact assessment
Resource recovery is crucial for small- and medium-sized enterprises to attain a circular economy. The economic benefits of recovering precious metals from electronic waste, such as waste printed circuit board...
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Article
Regioselective electrochemical radical cascade cyclization of internal alkynes to selenated and trifluoromethylated dihydropyran
Dihydropyran (DHP) compounds are not only found in natural products and bioactive molecules, but also serve as important precursors in organic synthesis. Nonetheless, traditional methods for the construction o...
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Article
The Robotic Arm Velocity Planning Based on Reinforcement Learning
In order to improve the performance of the robotic arm effectively, this study established a robotic arm velocity planning model developed by artificial intelligence in the simulation system. The model not onl...
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Open AccessPerformance of urinary C–C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis
Urinary C–C motif chemokine ligand 14 (CCL14) has been described as an effective marker for delayed recovery of acute kidney injury (AKI), yet its efficacy has been found to vary between different trials. The ...
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Article
Open AccessValve turning towards on-cycle in cobalt-catalyzed Negishi-type cross-coupling
Ligands and additives are often utilized to stabilize low-valent catalytic metal species experimentally, while their role in suppressing metal deposition has been less studied. Herein, an on-cycle mechanism is...
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Article
Open AccessCerebral Semaphorin3D is a novel risk factor for age-associated cognitive impairment
We previously reported that miR-195 exerts neuroprotection by inhibiting Sema3A and cerebral miR-195 levels decreased with age, both of which urged us to explore the role of miR-195 and miR-195-regulated Sema3...
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Open AccessAuthor Correction: Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy
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Open AccessActivation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol
No reports exist as to neuroprotective effects associated with topical activation of transient receptor potential melastatin 8 (TRPM8), a noted cold receptor. In the present study, we identified whether activa...
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Article
Open AccessEngineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy
PROteolysis TArgeting Chimeras (PROTACs) has been exploited to degrade putative protein targets. However, the antitumor performance of PROTACs is impaired by their insufficient tumour distribution. Herein, we ...
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Article
Open AccessAssociations of thiazide use with skin cancers: a systematic review and meta-analysis
Previous findings on the associations of thiazide use with skin cancers were conflicting. This study aimed to examine the associations of individual thiazide use with skin cancer risk, differentiated by subtyp...
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Article
Association between exposure to road traffic noise and hearing impairment: a case-control study
Noise pollution in urban areas is increasing steadily, and the study of road traffic noises and their effects on the auditory system was rare. This study investigated the potential effects of road traffic nois...
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Open AccessElectroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus
Post-traumatic stress disorder (PTSD) is a trauma-related disorder that is associated with pro-inflammatory activation and neurobiological impairments in the brain and leads to a series of affective-like behav...
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Open AccessElectroacupuncture prevents cocaine-induced conditioned place preference reinstatement and attenuates ΔFosB and GluR2 expression
Acupuncture has been used for treating drug addiction since the 1970s, but little is known about the mechanisms by which acupuncture affects drug cue-induced relapse. The transcription factor delta-FosB (ΔFosB...
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Article
Electrochemical oxidative aminocarbonylation of terminal alkynes
Palladium-catalysed oxidative carbonylation using oxygen as the oxidant is an economical approach; however, the gas mixture of CO and air has an explosive limit of 12.5–74.0% that could hamper extensive applic...
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Article
CO2 mineralization and utilization by alkaline solid wastes for potential carbon reduction
CO2 mineralization and utilization using alkaline solid wastes has been rapidly developed over the last ten years and is considered one of the promising technologies to stabilize solid wastes while combating glob...
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Article
Galantamine Inhibits Aβ1–42-Induced Neurotoxicity by Enhancing α7nAChR Expression as a Cargo Carrier for LC3 Binding and Aβ1–42 Engulfment During Autophagic Degradation
Despite Alzheimer’s disease (AD) being the most common neurodegenerative disorder worldwide, no FDA-approved disease-modifying treatments have been approved for this condition since 2003. Neuronal-type alpha7 ...
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Article
Open AccessInhibiting the LPS-induced enhancement of mEPSC frequency in superficial dorsal horn neurons may serve as an electrophysiological model for alleviating pain
Pain is a major primary health care problem. Emerging studies show that inhibition of spinal microglial activation reduces pain. However, the precise mechanisms by which microglial activation contributes to no...
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Article
Open AccessDirect electrochemical oxidation of alcohols with hydrogen evolution in continuous-flow reactor
Alcohol oxidation reactions are widely used for the preparation of aldehydes and ketones. The electrolysis of alcohols to carbonyl compounds have been underutilized owing to low efficiency. Herein, we report a...
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Article
Kinetic modeling of 1-decene oligomerization to synthetic fuels and base oil over tungstated-zirconia catalyst
The liquid phase oligomerization reaction of 1-decene to produce dimers and trimers was performed in a semi-batch autoclave reactor over a tungstated-zirconia catalyst at different reaction temperatures. While...
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Article
Phoenixin: a novel brain-gut-skin peptide with multiple bioactivity
In this brief review we summarize the current fndings relative to the discovery of a small peptide ligand, phoenixin (PNX). Using a bioinformatic approach, two novel peptides PNX-14 and PNX-20 containing 14 an...