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  1. Article

    Open Access

    Impact of respiratory bacterial infections on mortality in Japanese patients with COVID-19: a retrospective cohort study

    Although cases of respiratory bacterial infections associated with coronavirus disease 2019 (COVID-19) have often been reported, their impact on the clinical course remains unclear. Herein, we evaluated and an...

    Kensuke Nakagawara, Hirofumi Kamata, Shotaro Chubachi in BMC Pulmonary Medicine (2023)

  2. Article

    Open Access

    DOCK2 is involved in the host genetics and biology of severe COVID-19

    Identifying the host genetic factors underlying severe COVID-19 is an emerging challenge15. Here we conducted a genome-wide association study (GWAS) involving 2,393 cases of COVID-19 in a cohort of Japanese indi...

    Ho Namkoong, Ryuya Edahiro, Tomomi Takano, Hiroshi Nishihara, Yuya Shirai in Nature (2022)

  3. Article

    Open Access

    The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

    Coronavirus disease 2019 (COVID-19) is a recently-emerged infectious disease that has caused millions of deaths, where comprehensive understanding of disease mechanisms is still unestablished. In particular, s...

    Qingbo S. Wang, Ryuya Edahiro, Ho Namkoong, Takanori Hasegawa in Nature Communications (2022)

  4. Article

    Open Access

    Retrospective Study on the Effects of Glucose Abnormality on COVID-19 Outcomes in Japan

    To investigate the effects of glucose abnormality on outcomes of hospitalized coronavirus disease 2019 (COVID-19) patients in Japan.

    Yuya Nishida, Tomoya Mita, Makoto Hiki, Yasushi Matsushita in Diabetes Therapy (2022)

  5. Article

    Open Access

    Author Correction: Performance and usefulness of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit for the diagnosis of COVID-19

    Kaori Saito, Tomohiko Ai, Akinori Kawai, Jun Matsui in Scientific Reports (2021)

  6. Article

    Open Access

    Performance and usefulness of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit for the diagnosis of COVID-19

    Here, we aimed to evaluate the clinical performance of a novel automated immunoassay HISCL SARS-CoV-2 Antigen assay kit designed to detect the nucleocapsid (N) protein of severe acute respiratory syndrome coro...

    Kaori Saito, Tomohiko Ai, Akinori Kawai, Jun Matsui in Scientific Reports (2021)

  7. Article

    Open Access

    Clinical advantages of a newly launched anti-thrombotic PMMA membrane for the nutritional status and dialysis-related symptoms in older chronic dialysis patients: a multicenter pilot study

    Malnutrition that is associated with inflammation is a key factor of poor outcome in chronic hemodialysis patients, especially in older dialysis patients. Polymethyl methacrylate (PMMA) membrane has been repor...

    Ikuto Masakane, Ichiro Yamaguchi, Yuji Matsumoto, Ken Ataka in Renal Replacement Therapy (2021)

  8. Article

    Open Access

    Clinically feasible method for assessing leukocyte rheology in whole blood

    This study reports a novel method for assessment of leukocyte rheological activation with a new designed microchannel array chip to mimic the human microvascular network for microchannel array flow analysis (M...

    Riha Shimizu, Hirotsugu Fukuda, Yuji Kikuchi, Hirokazu Yanaka in Heart and Vessels (2020)

  9. No Access

    Article

    Radiographic analysis of pasteurized autologous bone graft

    Local malignant bone tumor excision followed by pasteurization and subsequent reimplantation is a unique technique for reconstruction after resection of primary bone sarcomas. The purpose of this investigation...

    Adel Refaat Ahmed, Jun Manabe, Noriyoshi Kawaguchi, Seiichi Matsumoto in Skeletal Radiology (2003)

  10. No Access

    Article

    Epithelioid sarcoma of the extremities: a dismal long-term outcome

     Epithelioid sarcoma is a rare histologic subtype of sarcoma. The clinical behavior and prognostic factors influencing survival in this disease are examined. A review of clinicopathologic features of patients ...

    Yasushi Matsushita, Adel Refaat Ahmed in Journal of Orthopaedic Science (2002)

  11. No Access

    Article

    Antitumor effects of oral administration of an interferon-inducing pyrimidinone, Bropirimine, on murine renal-cell carcinoma

    Bropirimine [2-amino-5-bromo-6-phenyl-4-(3H)-pyrimidinone] is a low-molecular-weight compound that acts as an inducer of interferon in several animal species. Experiments were designed to explore the possibili...

    Tomoaki Fujioka, Koich Ishikura, Michihiko Hasegawa in Cancer Chemotherapy and Pharmacology (1995)