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Article
Correction: A duplex structure of SARM1 octamers stabilized by a new inhibitor
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Article
A duplex structure of SARM1 octamers stabilized by a new inhibitor
In recent years, there has been growing interest in SARM1 as a potential breakthrough drug target for treating various pathologies of axon degeneration. SARM1-mediated axon degeneration relies on its TIR domai...
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Article
Open AccessPhosphatidylserine is a marker for axonal debris engulfment but its exposure can be decoupled from degeneration
Apoptotic cells expose Phosphatidylserine (PS), that serves as an “eat me” signal for engulfing cells. Previous studies have shown that PS also marks degenerating axonsduring developmental pruning or in respon...