75 Result(s)
within
Yao LI
Life Sciences
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Article
Open AccessGene identification, expression analysis, and molecular docking of SAT and OASTL in the metabolic pathway of selenium in Cardamine hu**shanensis
Identification of selenium stress-responsive expression and molecular docking of serine acetyltransferase (SAT) and O-acetyl serine (thiol) lyase (OASTL) in Cardamine hu**shanensis.
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Open AccessAuthor Correction: Ketogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy
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Decline in tree-ring growth of Picea mongolica and its intra-annual eco-physiological responses to drought and CO2 enrichment in semi-arid China
Episodes of drought-induced decline in tree growth and mortality are becoming more frequent as a result of climate warming and enhanced water stress in semi-arid areas. However, the ecophysiological mechanisms...
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Open AccessKetogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy
Ketogenic diet (KD) alleviates refractory epilepsy and reduces seizures in children. However, the metabolic/cell biologic mechanisms by which the KD exerts its antiepileptic efficacy remain elusive. Herein, we...
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Open AccessOptimization of preparation and transformation of protoplasts from Populus simonii × P. nigra leaves and subcellular localization of the major latex protein 328 (MLP328)
Populus simonii × P. nigra is an ideal material for studying the molecular mechanisms of woody plants. In recent years, research on Populus simonii × P. nigra has increasingly focused on the application of transg...
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Positive relationships between species diversity and genetic diversity on a local scale at Mt. Wu Yi, China
Variations of biodiversity levels are not always independent in the ecological processes driving community assembly. Recently, SGDC (Species–genetic diversity correlation) has been used to infer community asse...
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FBXL4 mutations cause excessive mitophagy via BNIP3/BNIP3L accumulation leading to mitochondrial DNA depletion syndrome
Mitochondria are essential organelles found in eukaryotic cells that play a crucial role in ATP production through oxidative phosphorylation (OXPHOS). Mitochondrial DNA depletion syndrome (MTDPS) is a group of...
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Open AccessQuartet protein reference materials and datasets for multi-platform assessment of label-free proteomics
Quantitative proteomics is an indispensable tool in life science research. However, there is a lack of reference materials for evaluating the reproducibility of label-free liquid chromatography-tandem mass spe...
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Open AccessShort-chain fatty acids in diseases
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate transporters, such a...
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Open AccessAn invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte–tumor cell crosstalk, local immunosuppression and tumor progression
Dissecting and understanding the cancer ecosystem, especially that around the tumor margins, which have strong implications for tumor cell infiltration and invasion, are essential for exploring the mechanisms ...
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Novel function of a putative TaCOBL ortholog associated with cold response
The plant COBRA protein family plays an important role in secondary cell wall biosynthesis and the orientation of cell expansion. The COBRA gene family has been well studied in Arabidopsis thaliana, maize, rice, ...
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Amino acids downregulate SIRT4 to detoxify ammonia through the urea cycle
Ammonia production via glutamate dehydrogenase is inhibited by SIRT4, a sirtuin that displays both amidase and non-amidase activities. The processes underlying the regulation of ammonia removal by amino acids ...
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Open AccessTranscriptional profiling of Xanthomonas campestris pv. campestris in viable but nonculturable state
Xanthomonas campestris pv. campestris (Xcc) is an important seed-borne plant pathogenic bacteria that can cause a serious threat to cruciferous crops. Bacteria can enter into the viable but non-culturable (VBNC) ...
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Open AccessSPOP inhibits BRAF-dependent tumorigenesis through promoting non-degradative ubiquitination of BRAF
The gene encoding the E3 ubiquitin ligase substrate-binding adapter Speckle-type BTB/POZ protein (SPOP) is frequently mutated in prostate cancer (PCa) and endometrial cancer (EC); however, the molecular mechanism...
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Article
Plant Growth Regulators Enhance Saline–Alkali Tolerance by Upregulating the Levels of Antioxidants and Osmolytes in Soybean Seedlings
Soil salinization has become a global problem and seriously endangers crop growth and yield improvement. In the present study, soybean (Hefeng 50) seedlings were used as test materials to study the mitigation ...
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Overexpression of a Phosphatidylinositol-Specific Phospholipase C Gene from Populus simonii × P. nigra Improves Salt Tolerance in Transgenic Tobacco
Phosphatidylinositol-specific phospholipase C (PI-PLC) catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate into diacylglycerol and inositol 1,4,5-trisphosphate. It can play an essential role in p...
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Open AccessExtracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage
Osteoarthritis (OA) is a prevalent degenerative joint disease that not only significantly impairs the quality of life of middle-aged and elderly individuals but also imposes a significant financial burden on p...
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Open AccessTSG-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress
Spinal cord ischemia reperfusion injury (SCIRI) is a complication of aortic aneurysm repair or spinal cord surgery that is associated with permanent neurological deficits. Mesenchymal stem cell (MSC)-derived s...
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Genome-wide analyses of introgression between two sympatric Asian oak species
Introgression can be an important source of new alleles for adaption under rapidly changing environments, perhaps even more important than standing variation. Though introgression has been extensively studied ...
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Host-plant volatiles enhance the attraction of Cnaphalocrocis medinalis (Lepidoptera: Crambidae) to sex pheromone
Cnaphalocrocis medinalis Guenée (Lepidoptera: Pyralidae) is a notorious pest of rice, Oryza sativa L. (Poaceae). Sex pheromones and host-plant volatiles can trap C. medinalis separately. To improve the trap effic...
