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Article
Open AccessCombinatorial macrophage induced innate immunotherapy against Ewing sarcoma: Turning “Two Keys” simultaneously
Macrophages play important roles in phagocytosing tumor cells. However, tumors escape macrophage phagocytosis in part through the expression of anti-phagocytic signals, most commonly CD47. In Ewing sarcoma (ES...
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Article
Open AccessDiversity analysis of sea anemone peptide toxins in different tissues of Heteractis crispa based on transcriptomics
Peptide toxins found in sea anemones venom have diverse properties that make them important research subjects in the fields of pharmacology, neuroscience and biotechnology. This study used high-throughput sequ...
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Article
Open AccessN6-methyladenosine demethylase FTO regulates synaptic and cognitive impairment by destabilizing PTEN mRNA in hypoxic-ischemic neonatal rats
Hypoxic-ischemic brain damage (HIBD) can result in significant global rates of neonatal death or permanent neurological disability. N6-methyladenosine (m6A) modification of RNA influences fundamental aspects o...
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Article
Open AccessRecognition and management of hemorrhaging in combination with emerging enterogenic sepsis during a hepatectomy: a case report
Patients with hemorrhagic shock may develop emerging enterogenic sepsis due to damage to the intestinal mucosal barrier and translocation of intestinal bacteria and endotoxins caused by ischemic injury. Becaus...
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Article
Experimental Study on Fabricating Micro-Hole Arrays on CVD Diamond Film Using a Nanosecond Pulsed Laser
The increasing demand for micro-parts and miniaturization of devices has led to development of manufacturing micro-holes on different materials. In this study, micro-hole arrays were drilled on a CVD diamond f...
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Article
Amitriptyline Protects Against Lidocaine-induced Neurotoxicity in SH-SY5Y Cells via Inhibition of BDNF-mediated Autophagy
Amitriptyline (AMI) is a traditional tricyclic antidepressant that has been proven to exhibit neuroprotective effects in various neurological disorders. However, the underlying mechanism by which AMI attenuate...
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Clinical Application of Umbilical Cord Blood-Derived Stem Cells for Tissue Regeneration
Cord blood transplantation has been utilized as an alternate allogeneic stem cell source for more than two decades for the treatment of a variety of malignant and nonmalignant diseases, including hematologic m...
