3 Result(s)

Article

Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation

Phosphorylation of IRF3 is critical to induce type I interferon (IFN-I) production in antiviral innate response. Here we report that lysine methyltransferase SMYD2 inhibits the expressions of IFN-I and proinfl...

Jiacheng Wu, Ye Hu, Jiaying Song, Jia Xu, Qian Zhang, Yangyang Chai… in Cell Death & Disease (2023)

Article

Disease profile and plasma neutralizing activity of post-vaccination Omicron BA.1 infection in Tian**, China: a retrospective study

Hong Zheng, Yunlong Cao, **aosu Chen, Fengmei Wang, Ye Hu, Weiliang Song… in Cell Research (2022)

Article

Chromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages

Transcription factor IRF3 is critical for the induction of antiviral type I interferon (IFN-I). The epigenetic regulation of IFN-I production in antiviral innate immunity needs to be further identified. Here, ...

Ye Hu, **n Wang, Jiaying Song, Jiacheng Wu, Jia Xu, Yangyang Chai… in Cell Death & Disease (2021)