4 Result(s)
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Yangyang Chai
Life Sciences
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Article
Open AccessLysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation
Phosphorylation of IRF3 is critical to induce type I interferon (IFN-I) production in antiviral innate response. Here we report that lysine methyltransferase SMYD2 inhibits the expressions of IFN-I and proinfl...
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Article
Open AccessDisease profile and plasma neutralizing activity of post-vaccination Omicron BA.1 infection in Tian**, China: a retrospective study
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Article
Structural analysis and in vitro antitumor effect of polysaccharides from Pholiota adiposa
Pholiota adiposa is an edible chestnut mushroom with many health benefits, such as antioxidant and anticancer activity. In this paper, polysaccharides were extracted from Pholidota adiposa using an acid extracti...
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Article
Open AccessChromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages
Transcription factor IRF3 is critical for the induction of antiviral type I interferon (IFN-I). The epigenetic regulation of IFN-I production in antiviral innate immunity needs to be further identified. Here, ...
