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Fructus Ligustri Lucidi (FLL) ethanol extract increases bone mineral density and improves bone properties in growing female rats

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  1. Article

    Open Access

    Phosphodiesterase 4D contributes to angiotensin II-induced abdominal aortic aneurysm through smooth muscle cell apoptosis

    Abdominal aortic aneurysm (AAA) is a permanent expansion of the abdominal aorta that has a high mortality but limited treatment options. Phosphodiesterase (PDE) 4 family members are cAMP-specific hydrolyzing e...

    Ran Gao, Wenjun Guo, Tianfei Fan, Junling Pang… in Experimental & Molecular Medicine (2022)

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  2. Article

    Open Access

    Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction

    Hypertension is a common chronic disease, which leads to cardio-cerebrovascular diseases, and its prevalence is increasing. The cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) pathway participates...

    Tianfei Fan, Yangfeng Hou, Weipeng Ge, Tianhui Fan, **aohang Feng… in Communications Biology (2022)

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