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Article
Associations Between Individual and Combined Metal Exposures in Whole Blood and Kidney Function in U.S. Adults Aged 40 Years and Older
The effects of metal exposure on kidney function have been reported in previous literature. There is limited and inconsistent information on the associations between individual and combined exposures to metals...
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Article
Exposure to PM2.5 and its five constituents is associated with the incidence of type 2 diabetes mellitus: a prospective cohort study in northwest China
Studies have demonstrated that fine particulate matter (PM2.5) is an underlying risk factor for type 2 diabetes mellitus (T2DM), but evidence exploring the relationship between PM2.5 chemical components and T2DM ...
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Article
Open AccessA study of temperature variability on admissions and deaths for cardiovascular diseases in Northwestern China
To explore the effect of temperature variability (TV) on admissions and deaths for cardiovascular diseases (CVDs).
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Article
Ambient temperature variability and blood pressure in a prospective cohort of 50,000 Chinese adults
Blood pressure has been shown to change by outdoor temperature, but whether intra- and inter-day temperature variability (TV) will bring higher effect on BP is not clear. Based on a prospective cohort study, t...
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Article
Prevalence of chronic kidney disease in a city of Northwestern China: a cross-sectional study
Chronic kidney disease (CKD) is increasingly recognized as a global health issue. There is a paucity of published data on the prevalence and risk factors of CKD in less-developed regions. This study aims to ev...
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Article
Associations between congenital heart disease and air pollutants at different gestational weeks: a time-series analysis
Exposure to air pollution during pregnancy has been linked to birth defects. But the directions of studies on the associations between air pollutants exposure and effect on the incidence of congenital heart di...
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Article
Association of air pollutants and hospital admissions for respiratory diseases in Lanzhou, China, 2014–2019
The aim of this study was to assess the effects of air pollutants on hospital admissions for respiratory disease (RD) by using distributed lag nonlinear model (DLNM) in Lanzhou during 2014–2019. In this study,...
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Article
Modeling methods for busulfan-induced oligospermia and asthenozoospermia in mice: a systematic review and meta-analysis
Modeling methods for busulfan-induced oligoasthenozoospermia are controversial. We aimed to systematically review the modeling method of busulfan-induced oligospermia and asthenozoospermia, and analyze changes...
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Article
Association between air pollutants and neural tube defects during pregnancy in Lanzhou, China: a time series analysis
Few studies have evaluated the association between air pollutants and neural tube defects (NTDs). Moreover, the existing research ignores the lag effect of air pollution on health and provides inconsistent epi...
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Article
The short-term effects of air pollutants on pneumonia hospital admissions in Lanzhou, China, 2014–2019: evidence of ecological time-series study
This study explored the short-term effects of air pollutants (PM2.5, PM10, SO2, NO2, O38h, and CO) on pneumonia-related hospital admissions in Lanzhou (an ex-heavily polluted city in Northwestern China). A time-s...
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Article
Time series analysis on association between ambient air pollutants and orofacial clefts during pregnancy in Lanzhou, China
Current studies on air pollutant exposure during pregnancy and orofacial clefts (OFCs) have inconsistent results, and few studies have investigated refined susceptible windows for OFCs. We aim to estimate asso...
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Article
Mediating effects of insulin resistance on the development of hypertension associated with elevated serum uric acid: a prospective cohort study
Many studies have demonstrated that elevated serum uric acid independently increases the risk of develo** hypertension. However, the role of insulin resistance in the relationship between serum uric acid and...
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Article
Interaction effect of blood glucose and pressure on the risk of chronic kidney disease: a population-based prospective cohort study
To evaluate the interaction effect of blood glucose and blood pressure on the risk of chronic kidney disease (CKD).
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Article
Cohort Profile Update: the China Metal-Exposed workers Cohort Study (**chang Cohort)
The **chang Cohort was an ongoing 20-year ambispective cohort with unique metal exposures to an occupational population. From January 2014 to December 2019, the **chang Cohort has completed three phases of f...
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Article
The effect and prediction of diurnal temperature range in high altitude area on outpatient and emergency room admissions for cardiovascular diseases
Diurnal temperature range (DTR) is a meteorological indicator closely associated with global climate change. Thus, we aim to explore the effects of DTR on the outpatient and emergency room (O&ER) admissions fo...
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Article
An effect of 24-hour temperature change on outpatient and emergency and inpatient visits for cardiovascular diseases in northwest China
Some studies suggested that 24-h temperature change (TC24) was one of the potential risk factors for human health. However, evidence of the short-term effect of TC24 on outpatient and emergency department (O&E...
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Article
Upregulated cyclins may be novel genes for triple-negative breast cancer based on bioinformatic analysis
Triple-negative breast cancer (TNBC) is one of the leading causes of death among females around the world. However, the molecular mechanism of the disease among TNBC patients remains to be further studied.
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Article
The association between gallstone disease (GSD) and the incidence of prediabetes and type 2 diabetes mellitus (type 2 DM): a prospective cohort study
The present study aimed to investigate the role of GSD in different phases of type 2 DM development in the **chang cohort study.
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Article
Metals compositions of indoor PM2.5, health risk assessment, and birth outcomes in Lanzhou, China
The study aimed to investigate the metal compositions in indoor PM2.5 and the potential health risks they pose to residents of an urban area in China. A total of 41 and 54 households were surveyed in February and...
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Article
Fertility among testicular cancer survivors: a case-control study in the U.S.
Testicular germ cell tumors (TGCT) disproportionately affect men between the ages of 15 and 49 years, when reproduction is typical. Although TGCT treatment directly affects gonadal tissues, it remains unclear ...