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Article
Amyloid and Tau as cerebrospinal fluid biomarkers in anti-N-Methyl-D-aspartate receptor encephalitis
Neuroinfection is associated with the deposition of amyloid-beta (Aβ) peptides, and subsequent decrease in cerebrospinal fluid (CSF) amyloid levels. However, whether autoimmune encephalitis involves extracellu...
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Article
Open AccessGenomic diversity of Yersinia pestis from Yunnan Province, China, implies a potential common ancestor as the source of two plague epidemics
Plague, caused by Yersinia pestis, is a zoonotic disease that can reemerge and cause outbreaks following decades of latency in natural plague foci. However, the genetic diversity and spread pattern of Y. pestis d...
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Article
Open AccessExperimental simulation of wormhole sanding cavity pattern and microscopic mechanism in heterogeneous weakly-cemented sandstone
Sand production has been a shared problem in the development of weakly-cemented sandstone oil reservoirs. Sanding simulation and prediction are of utmost importance for the production optimization of this type...
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Article
Open AccessSubversion of GBP-mediated host defense by E3 ligases acquired during Yersinia pestis evolution
Plague has caused three worldwide pandemics in history, including the Black Death in medieval ages. Yersinia pestis, the etiological agent of plague, has evolved a powerful arsenal to disrupt host immune defenses...
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Article
Comparative analysis of clinical and imaging data between patients with myelin oligodendrocyte glycoprotein antibody disease and patients with aquaporin 4 antibody-positive neuromyelitis optica spectrum disorder
We aimed to compare the clinical data, laboratory findings, and imaging characteristics of myelin oligodendrocyte glycoprotein antibody disease (MOGAD) and aquaporin 4 antibody (AQP4)-positive neuromyelitis op...
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Article
Open AccessNovel method to decrease the exposure time of the extraction string of the ureteral stent and its efficiency and safety verification in the clinic
Ureteral stent removal by an extraction string is advantageous. However, the increased risk of complications attributed to the continuous exposure of the string outside the urethra must be managed. This paper ...
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Article
Open AccessDevelopment and evaluation of an up-converting phosphor technology-based lateral flow assay for rapid and quantitative detection of Coxiella burnetii phase I strains
Coxiella burnetii is an obligate intracellular Gram-negative bacterium that causes a zoonotic disease commonly called Q fever globally. In this study, an up-converting phosphor technology-based lateral flow (UPT-...
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Article
Open AccessEvolutionary selection of biofilm-mediated extended phenotypes in Yersinia pestis in response to a fluctuating environment
Yersinia pestis is transmitted from fleas to rodents when the bacterium develops an extensive biofilm in the foregut of a flea, starving it into a feeding frenzy, or, alternatively, during a brief period directly...
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Article
Open AccessNeutralization of interleukin-17A alleviates burn-induced intestinal barrier disruption via reducing pro-inflammatory cytokines in a mouse model
The intestinal barrier integrity can be disrupted due to burn injury, which is responsible for local and systemic inflammatory responses. Anti-inflammation strategy is one of the proposed therapeutic approache...
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Article
Soft sweep development of resistance in Escherichia coli under fluoroquinolone stress
We employed a stepwise selection model for investigating the dynamics of antibiotic-resistant variants in Escherichia coli K-12 treated with increasing concentrations of ciprofloxacin (CIP). Firstly, we used Sang...
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Living Reference Work Entry In depth
Formal and Informal Care
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Article
Open AccessCharacterization of a novel class A carbapenemase PAD-1 from Paramesorhizobium desertii A-3-ET, a strain highly resistant to β-lactam antibiotics
Although clinical antibiotic-resistant bacteria have attracted tremendous attention in the microbiology community, the resistant bacteria that persist in natural environments have been overlooked for a longtim...
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Article
Open AccessGenomic characterization of novel IncFII-type multidrug resistant plasmids p0716-KPC and p12181-KPC from Klebsiella pneumoniae
This study aimed to genetically characterize two fully-sequenced novel IncFII-type multidrug resistant (MDR) plasmids, p0716-KPC and p12181-KPC, recovered from two different clinical Klebsiella pneumoniae isolate...
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Genome and Evolution of Yersinia pestis
This chapter summarizes researches on genome and evolution features of Yersinia pestis, the young pathogen that evolved from Y. pseudotuberculosis at least 5000 years ago. Y. pestis is a highly clonal bacterial s...
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Article
Open AccessTransmission efficiency of the plague pathogen (Y. pestis) by the flea, Xenopsylla skrjabini, to mice and great gerbils
Plague, a zoonotic disease caused by Yersinia pestis, is characterized by its ability to persist in the plague natural foci. Junggar Basin plague focus was recently identified in China, with Rhombomys opimus (gre...
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Article
Open AccessGeneral exponential dichotomies on time scales and parameter dependence of roughness
This paper focuses on a new notion called the general exponential dichotomy on time scales, which is more general and contains as special cases most versions of dichotomies on the continuous systems and discre...
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Article
Open AccessA bibliometric analysis of global forest ecology research during 2002–2011
Bibliometric is increasingly used for the analysis of discipline dynamics and management related decision-making. This study analyzes 937,923 keywords from 78,986 articles concerning forest ecology and conduct...
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Article
Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity
Mark Achtman and colleagues report the whole-genome sequencing of 11 Yersinia pestis isolates, the causative agent of the plague. Their phylogeographic analysis on a larger dataset of Y. pestis global isolates su...
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Article
Open AccessHigh-throughput bacterial SNP ty** identifies distinct clusters of SalmonellaTyphi causing typhoid in Nepalese children
Salmonella Typhi (S. Typhi) causes typhoid fever, which remains an important public health issue in many develo** countries. Kathmandu, the capital of Nepal, is an area of high incidence and the pediatric popu...
