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Article
Open AccessQuantitative and dynamic profiling of human gut core microbiota by real-time PCR
The human gut microbiota refers to a diverse community of microorganisms that symbiotically exist in the human intestinal system. Altered microbial communities have been linked to many human pathologies. Howev...
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Article
Open AccessProteogenomic discovery of sORF-encoded peptides associated with bacterial virulence in Yersinia pestis
Plague caused by Yersinia pestis is one of the deadliest diseases. However, many molecular mechanisms of bacterial virulence remain unclear. This study engaged in the discovery of small open reading frame (sORF)-...
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Article
Soft sweep development of resistance in Escherichia coli under fluoroquinolone stress
We employed a stepwise selection model for investigating the dynamics of antibiotic-resistant variants in Escherichia coli K-12 treated with increasing concentrations of ciprofloxacin (CIP). Firstly, we used Sang...
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Protocol
Online Resources for Yersinia pestis
The Internet provides rich resources for different kinds of pathogens, including Yersinia pestis. We collected different resources on various topics, including plague history, outbreak information, genome databas...
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Article
Open AccessCharacterization of a novel class A carbapenemase PAD-1 from Paramesorhizobium desertii A-3-ET, a strain highly resistant to β-lactam antibiotics
Although clinical antibiotic-resistant bacteria have attracted tremendous attention in the microbiology community, the resistant bacteria that persist in natural environments have been overlooked for a longtim...
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Article
Open AccessPlasmid pPCP1-derived sRNA HmsA promotes biofilm formation of Yersinia pestis
The ability of Yersinia pestis to form a biofilm is an important characteristic in flea transmission of this pathogen. Y. pestis laterally acquired two plasmids (pPCP1and pMT1) and the ability to form biofilms wh...
