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Article
Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Article
Insights into the effect of crystallinity on the sorption of organic pollutants to microplastics
The environmental behavior of microplastics (MPs) has attracted global attention. Research has confirmed that MPs can strongly absorb almost every kind of pollutant and can serve as vectors for pollutant trans...
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Article
Open AccessPhenotypic characterisation of regulatory T cells in patients with gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a common complication that occurs during pregnancy. Emerging evidence suggests that immune abnormalities play a pivotal role in the development of GDM. Specifically, regu...
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Article
Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health
The accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity, type 2 diabetes mellitus, heart failure, and non-alcoholic fatty liver disea...
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Chapter and Conference Paper
An Optimization Method for Parameter Adjustment of Pum** Well
In the process of oilfield development, due to changes in water injection adjustment, formation sand production, and formation pressure drop, the liquid production and dynamic liquid level of the oil well chan...
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Chapter and Conference Paper
Research and Practice of Digital Three-Phase Flowmeter for Complex Oil and Gas Occasion
In the development of oil and gas fields, the accurate measurement of oil, gas and water production rate is the basis for calculating the key parameters such as water cut (WCT) and gas-oil ratio (GOR), as well...
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Article
Open AccessGDF11 slows excitatory neuronal senescence and brain ageing by repressing p21
As a major neuron type in the brain, the excitatory neuron (EN) regulates the lifespan in C. elegans. How the EN acquires senescence, however, is unknown. Here, we show that growth differentiation factor 11 (G...
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Article
Open AccessNovel drug delivery strategies for antidepressant active ingredients from natural medicinal plants: the state of the art
Depression is a severe mental disorder among public health issues. Researchers in the field of mental health and clinical psychiatrists have long been faced with difficulties in slow treatment cycles, high rec...
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Article
Open AccessDistribution characteristics of organic carbon (nitrogen) content, cation exchange capacity, and specific surface area in different soil particle sizes
Understanding the distribution of soil organic carbon and nitrogen (OC(N)) content, cation exchange capacity (CEC), and specific surface area (SSA) in different soil particle sizes is crucial for studying soil...
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Article
FeCo-N encapsuled in nitrogen-doped carbon nanotubes as bifunctional electrocatalysts with a high stability for zinc air batteries
For zinc air batteries, a non-noble metal-based electrocatalyst with a high performance and stability in oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) is imperative in application. Herein...
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Article
Decreased GDF9 and BMP15 in follicle fluid and granulosa cells and outcomes of IVF-ET among young patients with low prognosis
To analyze the level of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) in follicle fluid (FF) and granulosa cells (GCs) derived from young patients with low prognosis for in vitr...
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Article
Recent progress of transition metal-based biomass-derived carbon composites for supercapacitor
Supercapacitors (SCs) have been considered as the most promising energy storage device due to high power density, long cycle life, and fast energy storage and efficient delivery. The excellent electrode materi...
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Article
Open AccessBiodegradable nanoplatform upregulates tumor microenvironment acidity for enhanced cancer therapy via synergistic induction of apoptosis, ferroptosis, and anti-angiogenesis
Chemodynamic therapy of cancer is limited by insufficient endogenous H2O2 generation and acidity in the tumor microenvironment (TME). Herein, we developed a biodegradable theranostic platform (pLMOFePt-TGO) invol...
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Article
Open AccessPDGFB-targeted functional MRI nanoswitch for activatable T1–T2 dual-modal ultra-sensitive diagnosis of cancer
As one of the most significant imaging modalities currently available, magnetic resonance imaging (MRI) has been extensively utilized for clinically accurate cancer diagnosis. However, low signal-to-noise rati...
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Article
Open AccessAn alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant
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Article
Blocked metabotropic glutamate receptor 5 enhances chemosensitivity in hepatocellular carcinoma and attenuates chemotoxicity in the normal liver by regulating DNA damage
DNA damaging agents are used as chemotherapeutics in many cancers, including hepatocellular carcinoma (HCC). However, they are associated with problems such as low sensitivity to chemotherapy and the induction...
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Article
Protective Mechanism of Electroacupuncture on Peripheral Neurotoxicity Induced by Oxaliplatin in Rats
To study the effect of electroacupuncture (EA) on oxaliplatin-induced peripheral neuropathy (OIPN) in rats.
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Article
Open AccessAbnormalities of Thalamic Functional Connectivity in Patients with Migraine: A Resting-State fMRI Study
Migraine is a common headache disorder. Many studies have used magnetic resonance imaging (MRI) to explore the possible pathogenesis of migraine, but they have not reached consistent conclusions and lack rigor...
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Article
The design of error-correcting output codes algorithm for the open-set recognition
The Open-Set recognition is an important topic in the pattern recognition research field. Different from the close-set recognition task, in the open-set recognition problem, the test data contains unknown clas...
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Article
Mitogenome of Knodus borki (Cypriniformes: Characidae): genomic characterization and phylogenetic analysis
The taxonomic status of Knodu in the family Characidae is not yet clear. This study aimed to address this by sequencing and annotating Knodu borki Zarske, 2008.
