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Transcriptome-guided resolution of tumor microenvironment interactions in pheochromocytoma and paraganglioma subtypes

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  1. Article

    ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease

    Aberrant chromatin remodeling is involved in the pathogenesis of Huntington's disease (HD) but the mechanism is not known. Herein, we report that mutant huntingtin (mtHtt) induces the transcription of alpha th...

    J Lee, Y K Hong, G S Jeon, Y J Hwang, K Y Kim, K H Seong… in Cell Death & Differentiation (2012)

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  2. Article

    Open Access

    Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis

    Colorectal cancer (CRC) is a leading cause of death in the United States. Increased level of interleukin-8 (IL-8) and CXCR2 on tumours and in the tumour microenvironment has been associated with CRC growth, pr...

    Y S Lee, I Choi, Y Ning, N Y Kim, V Khatchadourian, D Yang… in British Journal of Cancer (2012)

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  3. Article

    Open Access

    Inhibition of breast cancer growth in vivo by antiangiogenesis gene therapy with adenovirus-mediated antisense-VEGF

    Increased expression of VEGF in several types of tumours has been shown to correlate with poor prognosis. We used a replication-deficient adenoviral vector containing antisense VEGF cDNA (Ad5CMV-αVEGF) to down...

    S-A Im, J-S Kim, C Gomez-Manzano, J Fueyo, T-J Liu, M-S Cho… in British Journal of Cancer (2001)

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