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Article
DACH1 attenuated PA-induced renal tubular injury through TLR4/MyD88/NF-κB and TGF-β/Smad signalling pathway
Palmitic acid (PA), the major saturated fatty acid in the blood, often induces the initiation and progression of diabetic kidney disease (DKD). However, the underlying mechanism remains unclear. DACH1 is an im...
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Article
Building sustainability assessment model based on life cycle cost analysis and BIM technology
Architecture is one of the important factors that cause environmental pollution. This study aims to strengthen the application of green design concept in architecture, promote the sustainable development of ar...
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Article
A study of liquid argon detector’s n/ \(\gamma \) discrimination capability with PMT or SiPM readout
Liquid Argon (LAr) is used as a target material in several current and planned experiments related to dark matter direct searching and neutrino detection. Argon provides excellent pulse shape discrimination (P...
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Article
A bibliometric analysis of the toxicity research of carbon nanomaterials
Carbon nanomaterials (CNMs) are widely used, which has caused huge pressure on the ecological environment, especially human health. It is necessary to have a detailed understanding and real-time tracking of th...
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Article
Open AccessSTCF conceptual design report (Volume 1): Physics & detector
The super τ-charm facility (STCF) is an electron–positron collider proposed by the Chinese particle physics community. It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak lumino...
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Article
Develo** a single-phase liquid argon detector with SiPM readout
Liquid argon is used as a target material in several current and planned experiments related to dark matter direct searching and neutrino detection. SiPM is becoming the standard for scintillator detectors bec...
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Article
Free Vibration Analysis of Carbon-Nanotube-Reinforced Beams Resting on a Viscoelastic Pasternak Foundation by the Nonlocal Eshelby–Mori–Tanaka Method
The scale effect of carbon nanotubes (CNTs) in the macro CNT-reinforced composites (CNTRCs) is analyzed, and the free vibration characteristics of a CNT-reinforced composite beam resting on a viscoelastic foun...
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Chapter and Conference Paper
Experimental Study on the Dynamic Responses of a 2 MW Cross-Shaped Multi-Column Spar Floating Offshore Wind Turbine
In this study, a new conceptual cross-shaped multi-column spar foundation is proposed for floating offshore wind turbines. This foundation consists of a reinforced concrete cross pontoon, a central steel colum...
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Chapter and Conference Paper
Local Correlation and NpNn Linearity of Nuclear Electric Moments
In this work, we suggest that, as another important observable strongly related to nuclear structure evolution, the electric moment of the first 2+ state, denoted by Q here, is also governed by a similar local co...
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Article
Development of an Integrated Load Testing Device for a Substructure Hybrid Test of a Curved Bridge
A substructure hybrid test is an effective approach to reproduce the seismic behavior of engineering structures. The structure is partitioned into several substructures; those with complex behavior are analyze...
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Article
Nerve growth factor orchestrates NGAL and matrix metalloproteinases activity to promote colorectal cancer metastasis
Colorectal cancer (CRC) is one most cancer type of high incidence and high mortality rate. Metastasis play an important role in survival rate and life quality of colorectal cancer patients. Nerve growth factor...
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Chapter and Conference Paper
Fault Location Method of Multiple Bearings in Shafting Based on SPWVD-CNN
To solve the problem of multi-bearing fault diagnosis in mechanical equipment, it is necessary not only to confirm whether there is fault in shafting, but also to determine the position of the fault bearing, s...
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Article
Effect of Protein Supplementation Combined With Resistance Training on Muscle Mass, Strength and Function in the Elderly: A Systematic Review and Meta-Analysis
The loss of muscle mass, strength and function associated with increasing age has various health ramifications, including the elevated risk for falls, fractures, frailty, poor quality of life, and mortality. S...
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Article
Effect of Longitudinal Magnetic Field on Vibration Characteristics of Single-Walled Carbon Nanotubes in a Viscoelastic Medium
The effect of longitudinal magnetic field on vibration response of a sing-walled carbon nanotube (SWCNT) embedded in viscoelastic medium is investigated. Based on nonlocal Euler-Bernoulli beam theory, Maxwell’...
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Article
Open AccessRole of the adipose PPARγ-adiponectin axis in susceptibility to stress and depression/anxiety-related behaviors
Adaptive responses to stressful stimuli involving behavioral, emotional and metabolic changes are orchestrated by the nervous and endocrine systems. Adipose tissue has been recognized as a highly active metabo...
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Article
Open AccessInterleukin 33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma
Interleukin 33 (IL-33) represents a potential link between the airway epithelium and induction of Th2-type inflammatory responses associated with the development of asthma. This study investigated the potentia...
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Article
Free transverse vibration of double-walled carbon nanotubes embedded in viscoelastic medium
This paper aims to study the vibration characteristics of viscoelastic double-walled carbon nanotubes embedded in a viscoelastic medium. In doing this, the governing equations of the system are derived by comb...
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Article
EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1–TUFM protein complex
Epidermal growth factor receptor (EGFR)-targeted therapy in head and neck squamous cell carcinoma (HNSCC) patients frequently results in tumor resistance to treatment. Autophagy is an emerging underlying resis...
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Article
Open AccessAn ANCCA/PRO2000-miR-520a-E2F2 regulatory loop as a driving force for the development of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignancies in Asia especially in China. We previously identified that ANCCA/PRO2000 as an important proliferation-associated protein predicted poor pr...
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Article
HBV-induced ROS accumulation promotes hepatocarcinogenesis through Snail-mediated epigenetic silencing of SOCS3
Interleukin-6 (IL-6) has been demonstrated to be involved in Hepatitis B virus (HBV)-associated hepatocarcinogenesis through activation of the STAT3 pathway. The sustained activation of the IL-6/STAT3 pathway ...
