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  1. No Access

    Article

    Assessing the contribution of the chemical exposome to neurodegenerative disease

    Over the past few decades, numerous environmental chemicals from solvents to pesticides have been suggested to be involved in the development and progression of neurodegenerative diseases. Most of the evidence...

    S. Lefèvre-Arbogast, J. Chaker, F. Mercier, R. Barouki, X. Coumoul… in Nature Neuroscience (2024)

  2. No Access

    Article

    The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway

    The aryl hydrocarbon receptor (AhR) is commonly described as a transcription factor, which regulates xenobiotic-metabolizing enzymes. Recent studies have suggested that the binding of ligands to the AhR also a...

    C Tomkiewicz, L Herry, L-C Bui, C Métayer, M Bourdeloux, R Barouki, X Coumoul in Oncogene (2013)

  3. No Access

    Article

    Nedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticity

    Aryl hydrocarbon receptor (AhR), or dioxin receptor, is a transcription factor that induces adaptive metabolic pathways in response to environmental pollutants. Recently, other pathways were found to be altere...

    L -C Bui, C Tomkiewicz, A Chevallier, S Pierre, A -S Bats, S Mota, J Raingeaud… in Oncogene (2009)

  4. No Access

    Article

    Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism

    Environmental chemicals such as dioxin adversely affect immune, neurological and reproductive functions and have been implicated in cancer development. However, the mechanisms responsible for dioxin toxicity a...

    M Diry, C Tomkiewicz, C Koehle, X Coumoul, K Walter Bock, R Barouki, C Transy in Oncogene (2006)