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  1. Article

    Open Access

    A new antisarcoma strategy: multisubtype heat shock protein/peptide immunotherapy combined with PD-L1 immunological checkpoint inhibitors

    Osteosarcoma, a common malignant tumor in orthopedics, often has a very poor prognosis after lung metastasis. Immunotherapy has not achieved much progress in the treatment because of the characteristics of sol...

    H. Li, X. Sui, Z. Wang, H. Fu, Z. Wang, M. Yuan… in Clinical and Translational Oncology (2021)

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  2. Article

    Open Access

    Role of the active cycle of breathing technique combined with phonophoresis for the treatment of patients with chronic obstructive pulmonary disease (COPD): study protocol for a preliminary randomized controlled trial

    Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease characterized by coughing, the production of excess sputum, and dyspnea. Patients with excessively thick sputum may have freq...

    M. D. Shen, L. R. Guo, Y. W. Li, R. T. Gao, X. Sui, Z. Du, L. Q. Xu, H. Y. Shi… in Trials (2021)

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  3. No Access

    Article

    CD51 correlates with the TGF-beta pathway and is a functional marker for colorectal cancer stem cells

    Colorectal cancer (CRC) is one of the top three most prevalent and deadly cancers. A cancer stem cell (CSC) sub-population that is characterized by the abilities of tumor initiation, self-renewal, metastasis a...

    J Wang, B Zhang, H Wu, J Cai, X Sui, Y Wang, H Li, Y Qiu, T Wang, Z Chen, Q Zhu… in Oncogene (2017)

  4. Article

    Open Access

    Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

    Induction of cell death and inhibition of cell survival are the main principles of cancer therapy. Resistance to chemotherapeutic agents is a major problem in oncology, which limits the effectiveness of antica...

    X Sui, R Chen, Z Wang, Z Huang, N Kong, M Zhang, W Han, F Lou… in Cell Death & Disease (2013)

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  5. Article

    Generation of pancreatic insulin-producing cells from rhesus monkey induced pluripotent stem cells

    The generation of induced pluripotent stem cells (iPSCs) provides a promising possibility for type 1 diabetes therapy. However, the generation of insulin-producing cells from iPSCs and evaluation of their effi...

    F. F. Zhu, P. B. Zhang, D. H. Zhang, X. Sui, M. Yin, T. T. **ang, Y. Shi… in Diabetologia (2011)

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  6. No Access

    Article

    Hdm2 is regulated by K-Ras and mediates p53-independent functions in pancreatic cancer cells

    There is emerging evidence that the oncogenic potential of hdm2 (human and/or murine double minute-2 protein) stems not only from its ability to counteract tumor suppressor p53 but also from its less understoo...

    X Sui, S Shin, R Zhang, P F Firozi, L Yang, J L Abbruzzese, S A G Reddy in Oncogene (2009)