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Article
miR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis
Human cancers often exhibit attenuated microRNA (miRNA) biogenesis and global underexpression of miRNAs; thus, targeting the miRNA biogenesis pathway represents a novel strategy for cancer therapy. Here, we re...
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Article
Open AccessAutophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
Induction of cell death and inhibition of cell survival are the main principles of cancer therapy. Resistance to chemotherapeutic agents is a major problem in oncology, which limits the effectiveness of antica...
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Article
Open AccessNucleostemin mRNA is expressed in both normal and malignant renal tissues
Nucleostemin (NS), a p53-binding protein, has been shown essential for stem and cancer cell proliferation and implicated in oncogenesis. To explore potential contributions of NS to the development of clear cel...
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Chapter and Conference Paper
A parallel iterative solver for almost block-diagonal linear systems