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Article
Open AccessAssociation of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort
There is a lack of mechanism-driven, clinically relevant biomarkers in chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction, a proposed disease mechanism in COPD, is associated with the rele...
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Article
Open AccessIncreased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS
Levels of iron and iron-related proteins including ferritin are higher in the lung tissue and lavage fluid of individuals with chronic obstructive pulmonary disease (COPD), when compared to healthy controls. W...