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Article
Open AccessAssociation of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort
There is a lack of mechanism-driven, clinically relevant biomarkers in chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction, a proposed disease mechanism in COPD, is associated with the rele...
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Article
Increased platelet activation in sleep apnea subjects with intermittent hypoxemia
Obstructive sleep apnea (OSA) is independently associated with increased risk for stroke and other cardiovascular diseases. Since activated platelets play an important role in cardiovascular disease, the objec...
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Article
Open AccessIncreased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS
Levels of iron and iron-related proteins including ferritin are higher in the lung tissue and lavage fluid of individuals with chronic obstructive pulmonary disease (COPD), when compared to healthy controls. W...
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Article
Thrombotic risk factors in patients with antiphospholipid syndrome: a single center experience
Patients with primary or secondary antiphospholipid syndrome (APS) have an increased risk of recurrent venous, arterial thrombosis and pregnancy complications. Therefore, determining thrombotic risk is importa...
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Article
Open AccessAutomated expiratory ventilation assistance through a small endotracheal tube can improve venous return and cardiac output
Positive pressure ventilation can decrease venous return and cardiac output. It is not known if expiratory ventilation assistance (EVA) through a small endotracheal tube can improve venous return and cardiac o...
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Article
Delays in Initiating Post-operative Prophylactic Biologic Therapy Are Common Among Crohn’s Disease Patients
Studies have shown that prophylactic biologic therapy can reduce post-surgical Crohn’s disease recurrence.
