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    Article

    Plasma and cerebrospinal fluid pharmacokinetics of the novel tetrahydroisoquinoline EDL-155 in rats

    Tetrahydroisoquinolines (THIs) have demonstrated anti-cancer activity in rodent models of glioma, a form of brain cancer refractory to therapeutic intervention. In this study, peripheral and cerebrospinal flui...

    Pengfei Song, Fei Ma, Fan Wang, **angDi Wang in Cancer Chemotherapy and Pharmacology (2008)

  2. Article

    Open Access

    A functional profile of gene expression in ARPE-19 cells

    Retinal pigment epithelium cells play an important role in the pathogenesis of age related macular degeneration. Their morphological, molecular and functional phenotype changes in response to various stresses....

    Rajesh K Sharma, William E Orr, Allyson D Schmitt, Dianna A Johnson in BMC Ophthalmology (2005)