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  1. No Access

    Article

    Biological characterization of a chimeric mouse-human IgM antibody directed against the 17-1A antigen

    A chimeric antibody was constructed in which the murine H- and L-chain variable regions of mAb 17-1A, raised against human colorectal cancer cells, were joined with the human constant μ and κ regions. Transfec...

    William E. Fogler, Lee K. Sun, Mark R. Klinger… in Cancer Immunology, Immunotherapy (1989)

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    Article

    Efficient activation of human blood monocytes to a tumoricidal state by liposomes containing human recombinant gamma interferon

    Human recombinant gamma interferon (INF-γ) activated human peripheral blood monocytes to a cytotoxic state capable of lysing adherent tumorigenic cells without harming normal cells. The efficiency of INF-γ act...

    Wayne C. Koff, William E. Fogler, Jordan Gutterman… in Cancer Immunology, Immunotherapy (1985)

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    Article

    Toxicity studies of liposome-encapsulated immunomodulators administered intravenously to dogs and mice

    Multilamellar liposomes containing lymphokines from mitogen-stimulated rat lymphocytes were injected IV into BALB/c or (C57BL/6×C3H)F1 mice and Beagle dogs to evaluate their potential toxicity. Animals receive...

    Ian R. Hart, William E. Fogler, George Poste… in Cancer Immunology, Immunotherapy (1981)