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Article
Household Air Pollution in Three Urban Function Areas and Related Respiratory Health Effects
The health impact of atmospheric pollution is one of the hot topics in current environmental research. Herein, we examined the impacts of indoor and outdoor air pollution on respiratory health across three dis...
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Article
Open AccessGene gain and loss from the Asian corn borer W chromosome
Sex-limited chromosomes Y and W share some characteristics, including the degeneration of protein-coding genes, enrichment of repetitive elements, and heterochromatin. However, although many studies have sugge...
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Article
Disruption of cholangiocyte-B cell crosstalk by blocking the CXCL12-CXCR4 axis alleviates liver fibrosis
B cells can promote liver fibrosis, but the mechanism of B cell infiltration and therapy against culprit B cells are lacking. We postulated that the disruption of cholangiocyte-B-cell crosstalk could attenuate...
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Article
Open AccessAtypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration
Hepatocyte-cholangiocyte transdifferentiation (HCT) is a potential origin of proliferating cholangiocytes in liver regeneration after chronic injury. This study aimed to determine HCT after chronic liver injur...
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Article
Metabolic reprogramming in the OPA1-deficient cells
OPA1, a dynamin-related GTPase mutated in autosomal dominant optic atrophy, is essential for the fusion of the inner mitochondrial membrane. Although OPA1 deficiency leads to impaired mitochondrial morphology,...
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Article
Open AccessMolecular characteristics and stable carbon isotope compositions of dicarboxylic acids and related compounds in wintertime aerosols of Northwest China
Dicarboxylic acids are one of the important water-soluble organic compounds in atmospheric aerosols, causing adverse effects to both climate and human health. More attention has therefore been paid to organic ...
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Article
Self-supervised pairing image clustering for automated quality control
In manufacturing, artificial intelligence is attracting widespread attention to maximize industrial productivity. Image clustering, as a fundamental research direction in unsupervised learning, has been applie...
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Article
Open AccessEnrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1
Mitochondrial dysfunction is implicated in skeletal muscle insulin resistance. Syntaxin 4 (STX4) levels are reduced in human diabetic skeletal muscle, and global transgenic enrichment of STX4 expression improv...
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Article
Detection and segmentation of image anomalies based on unsupervised defect reparation
Anomaly detection is a challenging task in the field of data analysis, especially when it comes to unsupervised pixel-level segmentation of anomalies in images. In this paper, we present a novel multi-stage im...
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Article
Profiles and Source Apportionment of Nonmethane Volatile Organic Compounds in Winter and Summer in **’an, China, based on the Hybrid Environmental Receptor Model
Summer and winter campaigns for the chemical compositions and sources of nonmethane hydrocarbons (NMHCs) and oxygenated volatile organic compounds (OVOCs) were conducted in **’an. Data from 57 photochemical as...
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Article
Open AccessMitochondrial division inhibitor (mdivi-1) decreases oxidative metabolism in cancer
Previous studies suggested that mdivi-1 (mitochondrial division inhibitor), a putative inhibitor of dynamin-related protein (DRP1), decreased cancer cell proliferation through inducing mitochondrial fusion and...
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Article
Open AccessElevated CO2 concentration affects the defense of tobacco and melon against lepidopteran larvae through the jasmonic acid signaling pathway
The massive use of fossil fuels since the industrial revolution has led to a rapid increase in the concentration of carbon dioxide (CO2) in the atmosphere. What effects elevated CO2 concentrations (ECO2) have on ...
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Article
Open AccessOptimization of culture conditions for differentiation of melon based on artificial neural network and genetic algorithm
Artificial neural network is an efficient and accurate fitting method. It has the function of self-learning, which is particularly important for prediction, and it could take advantage of the computer’s high-s...
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Article
Open AccessCalcium chloride and 1-methylcyclopropene treatments delay postharvest and reduce decay of New Queen melon
In this study, newly harvested New Queen melons were treated with calcium chloride (CaCl2) and 1-methylcyclopropene (1-MCP) alone or in combination before storage. The results showed that the respiration rate, et...
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Article
Characteristics of single atmospheric particles in a heavily polluted urban area of China: size distributions and mixing states
To investigate the chemical composition, size distribution, and mixing state of aerosol particles on heavy pollution days, single-particle aerosol mass spectrometry was conducted during 9–26 October 2015 in **...
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Article
Open AccessUnderstanding the regulatory mechanisms of milk production using integrative transcriptomic and proteomic analyses: improving inefficient utilization of crop by-products as forage in dairy industry
Bovine milk is an important nutrient source for humans. Forage plays a vital role in dairy husbandry via affecting milk quality and quantity. However, the differences in mammary metabolism of dairy cows fed di...
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Article
Open AccessSource apportionment of VOCs and their impacts on surface ozone in an industry city of Baoji, Northwestern China
Level of surface ozone (O3) has been increasing continuously in China in recent years, while its contributors and formation pathways are less understood. In this study, distributions of volatile organic compounds...
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Article
Open AccessComplementary transcriptomic and proteomic analyses reveal regulatory mechanisms of milk protein production in dairy cows consuming different forages
Forage plays a critical role in the milk production of dairy cows; however, the mechanisms regulating bovine milk synthesis in dairy cows fed high forage rations with different basal forage types are not well-...
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Surface PM2.5, Satellite Distribution of Atmospheric Optical Depth and Related Effects on Crop Production in China
The surface concentrations of PM2.5 measured by the Chinese National Environmental Monitoring Center (CNEMC) and the aerosol optical depth (AOD) observed by the Moderate-Resolution Imaging Spectroradiometer (MODI...
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Article
Study on each phase characteristics of the whole coal life cycle and their ecological risk assessment—a case of coal in China
The paper divided the whole coal life cycle, explained each phase characteristics, and took coal mine in China as a study case to assess the ecological risk in coal utilization phase. The main conclusions are ...